Zinc Finger Nuclease (ZFN)

Introduction

Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.

Zinc finger nucleases (ZFNs)are enzymes which can be used to cleave DNA at select points, makes them useful tools for genetic engineering. ZFNs are composed of a DNA binding-domain and a DNA cleaving-domain.

The insertion code consists of:
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Filename: PHIL_1181_lores.jpg
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Legend/credit: Diagram of a zinc finger nuclease cleaving . Image credit to Stewart, C. N. and Burris, J. Jr.
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Other examples:
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Subscript: H₂O
Superscript: Fe³⁺

Section 1

Include some current research in each topic, with at least one figure showing data.

Section 2

Include some current research in each topic, with at least one figure showing data.

Section 3

Include some current research in each topic, with at least one figure showing data.

Conclusion

Overall paper length should be 3,000 words, with at least 3 figures.

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Porteus, M. H. and Carroll, D. "Gene targeting using zinc finger nucleases". Nature Biotechnology. 2005. Volume 23. p. 967-973.

Dana Carroll. "Genome engineering with zinc-finger nucleases". Genetics. 2011. Volume 188(4). p. 773–782.

Edited by student of Joan Slonczewski for BIOL 238 Microbiology, 2009, Kenyon College.