Microbial biofilm inhibits wound healing: Difference between revisions

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<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839004/pdf/wound.2011.0333.pdf Attinger, Christopher, and Randy Wolcott. “Clinically Addressing Biofilm in Chronic Wounds.” 2011. Advances in Wound Care, 1(3): 127-132. DOI: 10.1089/wound.2011.0333.]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839004/pdf/wound.2011.0333.pdf Attinger, Christopher, and Randy Wolcott. “Clinically Addressing Biofilm in Chronic Wounds.” 2011. Advances in Wound Care, 1(3): 127-132. DOI: 10.1089/wound.2011.0333.]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699762/pdf/fimmu-04-00143.pdf Duplantier, Allen J. and Monique L. Van Hoek. “The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds.” 2013. Frontiers in Immunology 4(143): 1-14. DOI: 10.3389/fimmu.2013.00143.]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530155/pdf/nihms419965.pdf Joo, Hwang-Soo and Michael Otto. “Molecular basis of In Vivo Biofilm Formation by Bacterial Pathogens.” 2012. Chemistry & Biology 19: 1503-1513. DOI: 10.1016/j.chembiol/2012.10.022.]</ref>
<ref>[https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0ahUKEwjDm6iqyJ3MAhXrnYMKHfWyDD0QFggdMAA&url=http%3A%2F%2Fwww.springer.com%2Fcda%2Fcontent%2Fdocument%2Fcda_downloaddocument%2F9781441960832-c1.pdf%3FSGWID%3D0-0-45-1012647-p173955914&usg=AFQjCNEWIyQYcpv4ljerLX9xv8xZWP-36A Kirketerp-Moller, Karen Zulkowski, and Garth James. “Chronic Wound Colonization, Infection, and Biofilms.” 2011. Biofilm Infections (Chapter 2). DOI: 10.1007/978-1-4419-6084-9_2.]</ref>


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Bacteria in biofilm are protected from antibiotic and host immune defenses. Source: Biofilms Made Easy,2010 1(1), Wounds International (http://www.woundsinternational.com/pdf/content_8851.pdf)].


By Katie Kaestner



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  1. ↑ Dowd, Scot E., Randall D. Wolcott, Yan Sun, Trevor McKeehan, Ethan Smith, and Daniel Rhoads. “Polymicrobial Nature of Chronic Diabetic Foot Ulcer Biofilm Infections Determined Using Bacterial Tag Encoded FLX Amplicon Pyrosequencing (bTEFAP).” 2008. PLoS ONE 3(10): e3326. DOI: 10.1371/journal.pone.0003326.
  2. ↑ Bertesteanu, Serban, Stefanos Triaridis, Milan Stankovic, Veronica Lazar, Mariana Carmen Chifiriuc, Mihaela Vlad, and Raluca Grigore. “Polymicrobial wound infections: Pathophysicology and current therapeutic approaches.” 2014. International Journal of Pharmaceutics 463: 119-126. DOI: 10.1016/j.ijpharm.2013.12.012.
  3. ↑ Attinger, Christopher, and Randy Wolcott. “Clinically Addressing Biofilm in Chronic Wounds.” 2011. Advances in Wound Care, 1(3): 127-132. DOI: 10.1089/wound.2011.0333.
  4. ↑ Duplantier, Allen J. and Monique L. Van Hoek. “The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds.” 2013. Frontiers in Immunology 4(143): 1-14. DOI: 10.3389/fimmu.2013.00143.
  5. ↑ Joo, Hwang-Soo and Michael Otto. “Molecular basis of In Vivo Biofilm Formation by Bacterial Pathogens.” 2012. Chemistry & Biology 19: 1503-1513. DOI: 10.1016/j.chembiol/2012.10.022.
  6. ↑ Kirketerp-Moller, Karen Zulkowski, and Garth James. “Chronic Wound Colonization, Infection, and Biofilms.” 2011. Biofilm Infections (Chapter 2). DOI: 10.1007/978-1-4419-6084-9_2.



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2016, Kenyon College.

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