Lemierre's Syndrome: Difference between revisions

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<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847443/ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847443/ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.]</ref>


<br> Information from review article<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176048/ Riordan T.. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre’s syndrome. Clin Microbiol Rev. 2007;20(4):622-59.]</ref><br>
<br> Similarly, exposure to the exogenous Fusobacterium necrophorum, which is not a part of normal throat flora does not always result in Lemierre’s syndrome; it can also result in tonsillitis, meningitis, and metastatic lesions, and a whole host of other issues (Fig. 2) <ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176048/ Riordan T.. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre’s syndrome. Clin Microbiol Rev. 2007;20(4):622-59.]</ref><br>
<br><br>A citation code consists of a hyperlinked reference within "ref" begin and end codes.
<br><br>A citation code consists of a hyperlinked reference within "ref" begin and end codes.


Revision as of 17:00, 21 April 2016

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Section

Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
Figure 1. The gram negative, anaerobic Fusobacterium necrophorum exhibiting bacilli morphology in a photomicrograph after being cultured for 48 hours in thioglycollate medium. Credit to CDC/ Dr. V. R. Dowell, Jr. in 1972. Image obtained from CDC Public Health Image Library.


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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Figure 2. Possible outcomes of infection with Fusobacterium necrophorum. The bacteria can cause a wide range of problems within the host, and this flowchart demonstrates the necessary intermediate steps to pass from one condition to another. Credit to Terry Riordan, 2007. Image obtained from Clin Microbiol Rev.


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Similarly, exposure to the exogenous Fusobacterium necrophorum, which is not a part of normal throat flora does not always result in Lemierre’s syndrome; it can also result in tonsillitis, meningitis, and metastatic lesions, and a whole host of other issues (Fig. 2) [3]


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Conclusion

References

  1. ↑ Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  2. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.
  3. ↑ Riordan T.. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre’s syndrome. Clin Microbiol Rev. 2007;20(4):622-59.



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2016, Kenyon College.

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