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2. [http://www.ijcmas.com/vol-4-3/Izumi%20Mashima,%20et%20al.pdf Mashima, I., Fujita, M., Nakatsuka, Y., Furuichi, Y., Herastuti,S., et al (2015) The Distribution and Frequency of Oral <i>Veillonella spp.</i>Associated with Chronic Periodontitis. Int J Curr Microbiol App Sci <b>4</b>(3): 150-160] | 2. [http://www.ijcmas.com/vol-4-3/Izumi%20Mashima,%20et%20al.pdf Mashima, I., Fujita, M., Nakatsuka, Y., Furuichi, Y., Herastuti,S., et al (2015) The Distribution and Frequency of Oral <i>Veillonella spp.</i>Associated with Chronic Periodontitis. Int J Curr Microbiol App Sci <b>4</b>(3): 150-160] | ||
3. [http://www.ncbi.nlm.nih.gov/nuccore/NC_013520.1] | 3. [http://www.ncbi.nlm.nih.gov/nuccore/NC_013520.1 NCBI Veillonella parvula DSM2008, complete genome] | ||
4. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374535/ Do, T., Sheehy, E. C., Mulli, T., Hughes, F., Beighton, D. (2015). Transcriptomic analysis of three Veillonella spp. present in carious dentine and in the saliva of caries-free individuals. Front Cell Infect Microbiol, <b>5</b>:25. doi: 10.3389/fcimb.2015.00025] | 4. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374535/ Do, T., Sheehy, E. C., Mulli, T., Hughes, F., Beighton, D. (2015). Transcriptomic analysis of three Veillonella spp. present in carious dentine and in the saliva of caries-free individuals. Front Cell Infect Microbiol, <b>5</b>:25. doi: 10.3389/fcimb.2015.00025] |
Revision as of 02:08, 11 September 2016
Emily Mantilla Bench B 31/08/2016 [1]
Classification
Higher order taxa
Prokaryote – Bacteria – Firmicutes – Negativicutes – Veillonellales – Veillonellaceae – Veillonella
Species
Veillonella parvula
Identified strains:
- Veillonella parvula AC2_8_11_AN_NA_2
- Veillonella parvula ACS-068-V-Sch12
- Veillonella parvula ATCC 17745
- Veillonella parvula DSM 2008
- Veillonella parvula HSIVP1
Description and significance
V. parvula is one of the six species belonging to the genus Veillonella which are gram-negative cocci and obligate anaerobes lacking capsule, spore or flagella [1]. This pathogen has been isolated from the periodontal pocket and has a role in dental plaque biofilm formation in the human oral cavity. V. parvula requires lactate as a nutrient source so it is commonly found in association with lactic-acid-producing species thus contributing to the cause of dental caries. Therefore it is established as the predominant species in subjects that have poor oral hygiene compared to those with moderate or good hygiene [1]. Moreover, it is found in the subgingival biofilm of patients with chronic periodontitis [2].
Genome structure
There is complete genome available from the NCBI for "V. parvula DSM 2008" (RefSeq NC_013520.1). The genome has a size of 2.13 Mb with 1,893 genes, 9 pseudo-genes and 3 frameshift genes. The GC content is 38.6% and encodes 1,822 proteins. There are 12 rRNA, 48 tRNA and 2 other RNA.
Cell structure and metabolism
Cell wall, biofilm formation, motility, metabolic functions.
Ecology
Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.
Pathology
V.parvula has been identified to have many pathogenic roles as well as being one of the organism responsible for bad mouthbreath. One study observed the distribution and frequency of oral Veillonella spp. and identified V. parvula as the predominant species in the subgingival biofilm of peridontal pockets and gingival sulcus in patients that presented chronic periodontitis [2]. Thus constituting a peridontal pathogen that facilitates the biofilm colonization of more pathogens of this type such as Porphyromonas gingivalis [2].
Application to biotechnology
Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…
Current research
Summarise some of the most recent discoveries regarding this species.
References
3. NCBI Veillonella parvula DSM2008, complete genome
- ↑ MICR3004
This page is written by Emily Mantilla for the MICR3004 course, Semester 2, 2016