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Rothia dentocariosa
Alexandria Chin, Bench C, 17 November 2024

Classification

Higher order taxa

Kingdom – Domain – Phylum – Class – Order – Family – Genus
Bacteria – Terrabacteria group – Actinobacteria – Actinobacteria – Micrococcales – Micrococcaceae – Rothia ^[1]

Species

Species name and type strain (consult LPSN http://www.bacterio.net/index.html for this information)

Rothia aeria (strain A1-17B), Rothia amarae (strain J18), Rothia dentocariosa (strain ATCC 17931), Rothia endophytica (strain YIM 67072), Rothia mucilaginosa (strain ATCC 25296), Rothia nasimurium (strain CCUG 35957), Rothia terrae (strain L-143) ^[2]

Description and significance

Give a general description of the species (e.g. where/when was it first discovered, where is it commonly found, has it been cultured, functional role, type of bacterium [Gram+/-], morphology, etc.) and explain why it is important to study this microorganism.

Type of bacterium: Gram-positive

Morphology: Coccoid to rod-shaped. Younger colonies are round, convex, smooth or creamy and potentially resembling corynebacteria and staphylococci. Mature colonies may be raised and highly convoluted. ^[4]

First discovered:

Commonly found: Mouth and respiratory tract

Cultured: yes

Functional role:

Importance: Morphologically similar to Actinomyces and Nocardia genus, which contain pathogenic members. ^[3]

Genome structure

Select a strain for which genome information (e.g. size, plasmids, distinct genes, etc.) is available.

Strain: ATCC 17931 ^[5] NCBI RefSeq: NC_014643.1

SIze: 2,506,025 bp

Topology: Circular

Chromosome: 1

Plasmids: 0

Genes:

• Total - 2,126
  • CDS - 2,040
• Protein - 2217
• RNA - 62
  • rRNA - 10
  • tRNA - 49
  • ncRNA - 3

Cell structure and metabolism

Cell wall, biofilm formation, motility, metabolic functions.

Cell wall:

Biofilm formation:

Motility: non-motile, non-sporogenic

Metabolic functions:

Reactions: catalase production, nitrate and nitrite reduction, esculin hydrolysis and acid production from glucose, sucrose, maltose, salicin and glycerol. ^[3]

Ecology

Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.

Aerobic ^[4]

Habitat: Oral cavity, teeth, other potential environments??

Microbe-host interactions:

Pathology

Do these microorganisms cause disease in the oral cavity or elsewhere?

Application to biotechnology

Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…

Current research

Summarise some of the most recent discoveries regarding this species.

References

1. NCBI Taxonomy Browser

2. List of Prokaryotic Names with Standing in Nomenclature

3. Brown, J.M., Georg, L.K., and Waters, L.C. (1969) Laboratory Identification of Rothia dentocariosa and Its Occurrence in Human Clinical Materials. Applied Microbiology 17(1): 150-156.

4. Ferraz, V., McCarthy, K., Smith, D., Koornhof, HJ. (1998) Rothia dentocariosa endocarditis and aortic root abscess. Journal of Infection 37(3): 292-295

5. Pathosystems Resource Integration Center

This page is written by Alexandria Chin for the MICR3004 course, Semester 2, 2016

Review

Lab identification and occurrence in human clinical materials