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==Description and significance== | ==Description and significance== | ||
''Veillonella parvula'' (''V. parvula'') first isolated by Veillon and Zuber in 1898 and falls under the 6 species of anaerobic gram-negative cocci under the genus ‘’Veillonella’’. | ''Veillonella parvula'' (''V. parvula'') first isolated by Veillon and Zuber in 1898 and falls under the 6 species of anaerobic gram-negative cocci under the genus ‘’Veillonella’’. <sup>[[#References|[1]]]</sup> | ||
''Veillonella parvula'' is a small and non-fermentative coccus that forms part of the normal flora of humans in the oropharynx (tongue,dental plaque, and the buccal mucosa, gastrointestinal tract and female genital tract and are harmless in general. Oral ''V. parvula'' plays a role in the early development of periodontal disease.<sup>[[#References|[2]]]</sup> ''V. parvula'' are rare opportunistic pathogens that are implicated in infections of sinuses, lungs, heart bone and central nervous system.<sup>[[#References|[1]]]</sup> ''V. parvula'' can coaggregate with other aerobic and anaerobic bacterias. With the ability of ''V. parvula'' to grow in a biofilm with other bacterium could allow the survival of other bacteria in antimicrobial treatment. Caries and periodontitis are polymicrobial disease where multiple bacterium plays a role and that the presence of ''V. parvula''gives other bacteria a survival advantage when undergoing antimicrobial treatment.<sup>[[#References|[3]]]</sup> | |||
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References examples | References examples | ||
1. [http:// | 1. [http://cid.oxfordjournals.org/content/31/3/839.x/full Bhatti, M. & Frank, M. (2000). Veillonella parvula Meningitis: Case Report and Review of Veillonella Infections. Clinical Infectious Diseases, 31(3), 839-840.] | ||
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2. [http://www.ncbi.nlm.nih.gov/pubmed/19828771.x/full Matera, G., Muto, V., Vinci, M., Zicca, E., Abdollahi-Roodsaz, S., & van de Veerdonk, F. et al. (2009). Receptor Recognition of and Immune Intracellular Pathways for Veillonella parvula Lipopolysaccharide. Clinical And Vaccine Immunology, 16(12), 1804-1809.] | |||
3. [http://www.ncbi.nlm.nih.gov/pubmed/18402603.x/full Luppens, S., Kara, D., Bandounas, L., Jonker, M., Wittink, F., & Bruning, O. et al. (2008). Effect of Veillonella parvula on the antimicrobial resistance and gene expression of Streptococcus mutans grown in a dual-species biofilm. Oral Microbiology And Immunology, 23(3), 183-189.] | |||
3. [http://cid.oxfordjournals.org/content/31/3/839.x/full Bhatti, M. & Frank, M. (2000). Veillonella parvula Meningitis: Case Report and Review of Veillonella Infections. Clinical Infectious Diseases, 31(3), 839-840.] | 3. [http://cid.oxfordjournals.org/content/31/3/839.x/full Bhatti, M. & Frank, M. (2000). Veillonella parvula Meningitis: Case Report and Review of Veillonella Infections. Clinical Infectious Diseases, 31(3), 839-840.] | ||
Revision as of 11:14, 21 September 2016
Name Chew Zi Huai (s4438663) Bench ID C Date 23/09/2016 [1]
Classification
Higher order taxa
Bacteria – Firmicutes – Negativicutes – Selenomonadales – Veillonellaceae – Veillonella
Species
Species name and type strain: Veillonella parvula DM2008
Description and significance
Veillonella parvula (V. parvula) first isolated by Veillon and Zuber in 1898 and falls under the 6 species of anaerobic gram-negative cocci under the genus ‘’Veillonella’’. [1]
Veillonella parvula is a small and non-fermentative coccus that forms part of the normal flora of humans in the oropharynx (tongue,dental plaque, and the buccal mucosa, gastrointestinal tract and female genital tract and are harmless in general. Oral V. parvula plays a role in the early development of periodontal disease.[2] V. parvula are rare opportunistic pathogens that are implicated in infections of sinuses, lungs, heart bone and central nervous system.[1] V. parvula can coaggregate with other aerobic and anaerobic bacterias. With the ability of V. parvula to grow in a biofilm with other bacterium could allow the survival of other bacteria in antimicrobial treatment. Caries and periodontitis are polymicrobial disease where multiple bacterium plays a role and that the presence of V. parvulagives other bacteria a survival advantage when undergoing antimicrobial treatment.[3]
Give a general description of the species (e.g. where/when was it first discovered, where is it commonly found, has it been cultured, functional role, type of bacterium [Gram+/-], morphology, etc.) and explain why it is important to study this microorganism. Examples of citations [1], [2]
Genome structure
Veillonella parvula DSM 2008 has one main circular DNA chromosome with 38.6% GC content. With a total of 2132142 base pair, 1920 predicted genes, 1859 protein genes, 61 RNA genes and 15 pseudogenes.
Cell structure and metabolism
Cell wall, biofilm formation, motility, metabolic functions.
Ecology
Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.
Pathology
Do these microorganisms cause disease in the oral cavity or elsewhere?
Application to biotechnology
Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…
Current research
Summarise some of the most recent discoveries regarding this species.
References
References examples
- ↑ MICR3004
This page is written by<Chew Zi Huai> for the MICR3004 course, Semester 2, 2016
