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1. [http://onlinelibrary.wiley.com/doi/10.1046/j.1462-2920.1999.00007.x/full Sahm, K., MacGregor, B.J., Jørgensen, B.B., and Stahl, D.A. (1999) Sulphate reduction and vertical distribution of sulphate-reducing bacteria quantified by rRNA slotblot hybridization in a coastal marine sediment. Environ Microbiol <b>1</b>: 65-74.] | 1. [http://onlinelibrary.wiley.com/doi/10.1046/j.1462-2920.1999.00007.x/full Sahm, K., MacGregor, B.J., Jørgensen, B.B., and Stahl, D.A. (1999) Sulphate reduction and vertical distribution of sulphate-reducing bacteria quantified by rRNA slotblot hybridization in a coastal marine sediment. Environ Microbiol <b>1</b>: 65-74.] | ||
2. [http://www.homd.org Human Oral Microbiome] | 2. [http://journal.frontiersin.org/article/10.3389/fmicb.2016.00053/full How, K. Y., Song, K. P. and Chan, K. G. (2016) Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line. Front Microbiol, <b>7<b>: 53.] | ||
3. [http://www.homd.org Human Oral Microbiome] | |||
4. [http://jcm.asm.org.ezproxy.library.uq.edu.au/content/47/10/3073 Igboin, C. O., Griffen, A. L. and Leys, E. J. (2009) Porphyromonas gingivalis strain diversity. J Clin Microbiol, <b>47,<b>: 3073-81.] | |||
<references/> | <references/> | ||
This page is written by Louise Parker for the MICR3004 course, Semester 2, 2016 | This page is written by Louise Parker for the MICR3004 course, Semester 2, 2016 |
Revision as of 04:27, 23 September 2016
Louise Parker Bench D 31/08/2016 [1]
Classification
Higher order taxa
Bacteria – Domain – Bacteroidetes – Bacteroidetes – Bacteroidales – Porphyromonadaceae – Porphyromonas
Species
Species: Porphyromonas gingivalis
Strain: strain 2561 = ATCC 33277= CCUG 25893 = CCUG 25928 = CIP 103683 = DSM 20709 = JCM 12257 = NCTC 11834.
Description and significance
Give a general description of the species (e.g. where/when was it first discovered, where is it commonly found, has it been cultured, functional role, type of bacterium [Gram+/-], morphology, etc.) and explain why it is important to study this microorganism. Examples of citations [1], [2]
Porphyromonas gingivalis is a Gram-negative anaerobe. It is a major causative agent of the initiation and progression of periodontal disease, a main cause of tooth loss [1]. It is often found in deep periodontal pockets.
Genome structure
Select a strain for which genome information (e.g. size, plasmids, distinct genes, etc.) is available.
The Porphyromonas gingivalis strain W83 has a 2,343,479bp genome sequence. It has an average G+C content of 48.3%. 1,990 open reading frames were identified in the genome, making up 85% of the genome. 1,075 of these were assigned biological role categories. - (Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83)Distinct genes
Cell structure and metabolism
Cell wall, biofilm formation, motility, metabolic functions.
Ecology
Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.
Pathology
Do these microorganisms cause disease in the oral cavity or elsewhere?
Application to biotechnology
Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…
Current research
Summarise some of the most recent discoveries regarding this species.
References
bold number - issue/volume?
Reference examples
- ↑ MICR3004
This page is written by Louise Parker for the MICR3004 course, Semester 2, 2016