Bacteroides fragilis: Difference between revisions

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==Introduction==
==Introduction==
<i>Bacteroides fragilis</i> (BF) is a Gram-negative bacterium found in the human colon (1). It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality (2). In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. (3) This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.<br><br>
<i>Bacteroides fragilis</i> (BF) is a Gram-negative bacterium found in the human colon [[#References|[1]]]. It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality [[#References|[2]]]. In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. [[#References|[3]]] This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.<br><br>


Source 1: Kuwahara, Tomomi, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.<br><br>


Source 2: Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.<br><br>
[[Image:Bacteroides_fragilis.jpg|thumb|300px|right|Colony of <i>Bacteroides fragilis</i>, Gram-stained and magnified 1000x.  Image taken by Don Stalon. Source: [https://phil.cdc.gov/Details.aspx?pid=11198 Centers for Disease Control and Prevention]]]
 
Source 3: Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.<br><br>
[[Image:Bacteroides_fragilis.jpg|thumb|300px|right|Colony of <i>Bacteroides fragilis</i>, Gram-stained and magnified 1000x.  Image taken by Don Stalon.]]


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<br>At right is a sample image insertion.  It works for any image uploaded anywhere to MicrobeWiki.  The insertion code consists of:
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==References==
==References==
[1] Kuwahara, Tomomi, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.<br><br>
[2] Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.<br><br>
[3] Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.<br><br>
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Revision as of 13:12, 11 November 2019

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Introduction

Bacteroides fragilis (BF) is a Gram-negative bacterium found in the human colon [1]. It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality [2]. In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. [3] This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.


Colony of Bacteroides fragilis, Gram-stained and magnified 1000x. Image taken by Don Stalon. Source: Centers for Disease Control and Prevention


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References

[1] Kuwahara, Tomomi, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.

[2] Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.

[3] Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.


Edited by James Cawthon, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.