Clostridium limosum: Difference between revisions

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=2. Description and significance=
=2. Description and significance=
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
Clostridium limosum is a Gram-positive bacterium that has large, straight, rod-shaped cells. C. limosum is found in soil, but it has also been known to infect humans and animals such as cattle, farm minks, and chickens (2) (3). The pathogenic properties are still a source of current research as the route of transmission is not fully understood, with a special focus on potential foodborne illness, because of the clinical disease implications in livestock (2) (4). C. limosum is a close relative of Clostridium botulinum, the bacteria that cause the illness of botulism via a toxin that attacks the nervous system (2). However, treatment for botulism does not successfully treat a C. limosum infection, making the comparison between the two a source of interest (2). There is previous evidence of human infection in lung abscesses as a part of a mixed infection (5) (6). C. limosum infections within humans are known to be exceedingly rare, but carry a large risk of future complications and occasionally death (6).
*Include as many headings as are relevant to your microbe. Consider using the headings below, as they will allow readers to quickly locate specific information of major interest*
 
=3. Genome structure=
=3. Genome structure=
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?

Revision as of 14:33, 6 December 2021

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1. Classification

a. Higher order taxa

Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae; Hathewaya (1)

2. Description and significance

Clostridium limosum is a Gram-positive bacterium that has large, straight, rod-shaped cells. C. limosum is found in soil, but it has also been known to infect humans and animals such as cattle, farm minks, and chickens (2) (3). The pathogenic properties are still a source of current research as the route of transmission is not fully understood, with a special focus on potential foodborne illness, because of the clinical disease implications in livestock (2) (4). C. limosum is a close relative of Clostridium botulinum, the bacteria that cause the illness of botulism via a toxin that attacks the nervous system (2). However, treatment for botulism does not successfully treat a C. limosum infection, making the comparison between the two a source of interest (2). There is previous evidence of human infection in lung abscesses as a part of a mixed infection (5) (6). C. limosum infections within humans are known to be exceedingly rare, but carry a large risk of future complications and occasionally death (6).

3. Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?

4. Cell structure

Interesting features of cell structure. Can be combined with “metabolic processes”

5. Metabolic processes

Describe important sources of energy, electrons, and carbon (i.e. trophy) for the organism/organisms you are focusing on, as well as important molecules it/they synthesize(s).

6. Ecology

Habitat; symbiosis; contributions to the environment.

7. Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

8. Current Research

Include information about how this microbe (or related microbes) are currently being studied and for what purpose

9. References

It is required that you add at least five primary research articles (in same format as the sample reference below) that corresponds to the info that you added to this page. [Sample reference] Faller, A., and Schleifer, K. "Modified Oxidase and Benzidine Tests for Separation of Staphylococci from Micrococci". Journal of Clinical Microbiology. 1981. Volume 13. p. 1031-1035.