Micrococcus luteus: Difference between revisions
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==Cell Structure, Metabolism and Life Cycle== | ==Cell Structure, Metabolism and Life Cycle== | ||
''M. luteus'' are gram positive, non-motile, spherical cells that form tetrads and clusters. It utilizes sugars for energy and produces glutamic acid, thiosulphate, and polyhydroxybutyrate (PHB). It also supports the biosynthesis of alkene and carotenoids. | |||
==Ecology and Pathogenesis== | ==Ecology and Pathogenesis== | ||
Revision as of 18:07, 15 November 2022
Classification
Bacteria; Terrabacteria; Actinobacteria; Actinomycetia; Micrococcales; Micrococcaceae; Micrococcus
Species
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NCBI: [1] |
Micrococcus luteus
Description and Significance
Micrococcus luteus is a oligotrophic bacteria that can be found on the skin of humans and other mammals, some foods, soil, and water. This aerobic microorganism can withstand severe and unfavorable conditions, but is not spore-forming. Instead it uses resuscitation promoting factor (Rpf) to revive itself from dormancy.
M. luteus is considered part of the normal microbiota and plays a role in breaking down the compounds in sweat which produces body-odor.
Genome Structure
The “Fleming strain,” NCTC2665, is a single circular chromosome. It is one of the smallest actinobacterial genomes ever sequenced. It has 2,501,097 base pairs and G+C content of 73%. It Is thought that it can encode for 2,403 proteins. Despite its small size it contains 73 insertion sequence (IS) elements. However, it only encodes for four sigma factors and 14 response regulators. It is predicted that this is a result of keeping a strict niche of mammalian skin.
Cell Structure, Metabolism and Life Cycle
M. luteus are gram positive, non-motile, spherical cells that form tetrads and clusters. It utilizes sugars for energy and produces glutamic acid, thiosulphate, and polyhydroxybutyrate (PHB). It also supports the biosynthesis of alkene and carotenoids.
Ecology and Pathogenesis
M. luteus is present on human skin and it forms a commensal relationship here. Under normal conditions M. luteus is non-pathogenic and has low virulence factors. However, it is also considered an opportunistic pathogen. This means that it can cause infections in immunocompromised patients or those with poor hygiene. M. luteus has been linked with several illnesses including meningitis, septic arthritis, endocarditis, chronic cutaneous infections in HIV positive patients, and catheter infections.
References
Author
Page authored by Brittney Moore, student of Prof. Bradley Tolar at UNC Wilmington.
