Whooping Cough
Background
Pathogenesis
Current Vaccine Options
DwP Vaccine
DaP Vaccine
Recent Vaccine Failures
Incidents
Differences in Vaccine Efficacy
Other Hypotheses for the Failures
The Search for Improvement
References
1. "Pertussis Vaccines: WHO Position Paper." Weekly Epidemiological Record 85.40 (2010): 385-400. Academic Search Premier. Web. 26 Feb. 2015.
2. Clark, Thomas A. "Changing Pertussis Epidemiology: Everything Old is New Again." The Journal of Infectious Diseases 209.7 (2014): 978-981. Web. 26 Feb. 2015.
3. Klein, Nicola P., Joan Bartlett, Bruce Fireman, Ali Rowhani-Rahbar, and Roger Baxter. "Comparative Effectiveness of Acellular Versus Whole-Cell Pertussis Vaccines in Teenagers." Pediatrics. 131.6 (2013): 1716-1722. Web. 26 Feb. 2015.
4. Riolo, Maria A., Aaron A. King, and Pejman Rohani. "Can vaccine legacy explain the British pertussis resurgence?" Vaccine. 31(2013): 5903-5908. Web. 26 Feb. 2015.
5. Robbins, John B., Rachel Schneerson, Joanna Kubler-Kielb, Jerry M. Keith, Birger Trollfors, Evgeny Vinogradov, and Joseph Shiloach. "Toward a new vaccine for pertussis." PNAS. 111.9 (2014): 3213-3216. Web. 26 Feb. 2015.
6. Donnelly, Sheila, Christine E. Loscher, Marina A. Lynch, and Kingston H.G. Mills. “Whole-Cell but Not Acellular Pertussis Vaccines Induce Convulsive Activity in Mice: Evidence of a Role for Toxin-Induced Interleukin-1β in a New Murine Model for Analysis of Neuronal Side Effects of Vaccination.” Infection and Immunity. 69.7 (2001): 4217-4223. Web. 15 Mar. 2015.
7. Mattoo, Seema and James D. Cherry. “Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and other Bordetella Subspecies.” Clinical Microbiology Reviews. 18.2 (2005): 326-382. Web. 15 Mar. 2015
8. Fine, Paul E. M. and Jacqueline A. Clark. “Reflections on the Efficacy of Pertussis Vaccines.” Reviews of Infectios Diseases. 9.5 (1987): 866-883. Web. 15 Mar. 2015
Edited by Kristina Millar, a student of Nora Sullivan in BIOL168L (Microbiology) in The Keck Science Department of the Claremont Colleges Spring 2014.