Smallpox Virus

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Template:Smallpox Virus Curated

Description

The variola virus is a rather large, rectangular shaped, double-stranded DNA pathogen. Unique from other DNA viruses, the variola virus replicates in the cytoplasm of parasitized host cells. Smallpox is capable of solely infecting humans and does not exist in a carrier state.The virus is capable of surviving in environments for a short period of time, and has maximum stability at low humidity and temperatures. Variola is most efficiently spread by inhalation and less effectively by direct contact with scabs or puss from infected skin lesions.

Pathogenesis

Clinical Features and Diagnosis

Socioeconomic Impact

The first appearance of smallpox lesions were found from Egyptian mummies including Pharaoh Ramses V who died in 1157 BC, although it is believed to have first invaded the earth around 10,000 BC. The first recorded epidemic of smallpox was in 1350 BC. The World Health Organization officially announced the world clear of the smallpox virus in 1980. This was the first disease to be eradicated by scientific effort. Throughout the twentieth century, 

References

Created by Danielle Lewis