User:S4414061
Esther Chua | Bench E | 31 Aug 2016 [1]
Classification
Higher order taxa
Bacteria - Proteobacteria - Betaproteobacteria - Neisseriales - Neisseriaceae - Kingella - Kingella oralis
Species
Kingella oralis
Type strain: strain UB-38 = ATCC 51147= CCUG 30450 = CIP 103803
Description and significance
Kingella oralis was originally described by Chen et al.(1990) AS Eikenella corrodens -like isolates. In the original 1993 classification paper, this species was named K. orale, but the spelling was changed to "oralis" in 1994 (Dewhirst et at., 1993,1994). K. oralis are gram-negative facultative (aerobic and anaerobic growth) organism thats grows in mesophillic environments and is isolated from human dental plaque. Kingella oralis is associated with periodontitis;
Genome structure
Kingella Oralis strain ATCC 51147 does not encode for chromosomes and plasmids. It has a total length of about 2.41mb, encodes for 2,315 proteins and has a GC content of 54.3%. Sequencing results show that ATCC51147 consists of 5 scaffolds (Scfld 0-4) with no gaps between, an assembly gap length of 700, and 12 contigs. It has 3,165 coding genes and 52 non-coding genes. However the functions of these genes are not yet known.
This strain has contains specialty genes that are of particular interest, such as antibiotic resistance genes, drug targets, virulence factors, and human homologs.
Select a strain for which genome information (e.g. size, plasmids, distinct genes, etc.) is available.
Cell structure and metabolism
Cell wall, biofilm formation, motility, metabolic functions.
Kingella oralis are gram negative rods or cocobacilli that can form pairs or chains. It has a cell wall that consists of an outer membrane containing lipopolysaccharides, a periplasmic space with a peptidoglycan layer, and an inner, cytoplasmic membrane. Cells have monopolar fimbriae and form spreading colonies. Cells can be aerobic or facultatively anaerobic.
They are oxidase positive and catalase negative
Ecology
Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.
Pathology
Do these microorganisms cause disease in the oral cavity or elsewhere?
Application to biotechnology
Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…
Current research
Summarise some of the most recent discoveries regarding this species.
References
1. (2016) Kingella oralis (ID 1949)-Genome-NCBI 2. Yagupsky, P. Kingella species. Antimicrobe
References examples
- ↑ MICR3004
This page is written by <Esther Chua> for the MICR3004 course, Semester 2, 2016