Capnocytophaga canimorsus
Classification
Domain; Phylum; Class; Order; family [Others may be used. Use NCBI link to find]
Species
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NCBI: [1] |
Genus species
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
Genome Structure
The genome of C. canimorsus consists of a single, circular chromosome that is approximately 2.8 million base pairs long, with 36.11% of its content being guanine and cytosine. It additionally contains 2,405 CDSs. The genome size of C. canimorsus is most similar to Capnocytophaga ochracea, a bacteria found in the mouths of dogs and cats since it has 2.6 million base pairs. C. canimorsus contains 206 lipoprotein genes which is unusually high among Eubacteria and encodes the LolACDE lipoprotein export system to help transport these lipoproteins.
The genome does not encode type III, IV, or VI secretion systems which are commonly linked to pathogenesis. However, it does produce the enzyme protease, CcDPP7, which causes factor X dysfunction by N-terminal cleavage and promotes immune evasion and triggers hemorrhage.
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
Author
Page authored by _____, _____, _____, & _____, students of Prof. Bradley Tolar at UNC Wilmington.
