Actinobacillus pleuropneumoniae
Classification
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Pasteurellales
Family: Pasteurellaceae
Genus: Actinobacillus
Species: pleuropneumoniae
Actinobacillus pleuropneumoniae
Description and Significance
Actinobacillus pleuropneumoniae (App, previously Haemophilus pleuropneumoniae), is a Gram-negative, facultative anaerobic, respiratory pathogen found in pigs. It was first reported in 1957, and was formally declared to be the causative agent of porcine pleuropneumonia in 1964.It was reclassified in 1983 after DNA studies showed that it was more closely related to Actinobacillus lignieresii. [1]
Structure, Metabolism, and Life Cycle
A. pleuropneumoniae is a non-motile, Gram-negative, encapsulated coccobacillus bacteria found in the Pasteurellaceae family. It exhibits β-hemolysis activity, thus explaining its growth on chocolate or blood agar, but must be supplemented with V factor (NAD) in order to facilitate growth for one of its biological variants. As a facultative anaerobic pathogen, A. pleuropneumoniae may need CO2 in order to grow.Depending on the biovar, the bacteria may or may not be positive for urease; both biovars are positive for porphyrin.
Ecology and Pathogenesis
Natural habitat (soil, water, commensal of humans or animals?)
If relevant, how does this organism cause disease? Human, animal, or plant hosts? Important virulence factors, as well as patient symptoms.
References
[1] EXAMPLE ONLY. REPLACE WITH YOUR REFERENCES. Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. 2000. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 50: 489-500. http://ijs.sgmjournals.org/cgi/reprint/50/2/489
Author
Page authored by Kejun Shao, student of Mandy Brosnahan, Instructor at the University of Minnesota-Twin Cities, MICB 3301/3303: Biology of Microorganisms.
