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Rothia dentocariosa
Alexandria Chin, Bench C, 17 November 2024

Classification

Higher order taxa

Bacteria – Terrabacteria group – Actinobacteria – Actinobacteria – Micrococcales – Micrococcaceae – Rothia ^[1]

Species

Rothia dentocariosa
Type strain: strain ATCC 17931= CCUG 35437 = CIP 81.83 = DSM 43762 = DSM 46363 = IFO (now NBRC) 12531 = JCM 3067 = NCTC 10917 = NRRL B-8017. ^[2]

Description and significance

First discovered:

Commonly found: Mouth and respiratory tract

Type of bacterium: Gram-positive

Morphology: Coccoid to rod-shaped. Younger colonies are round, convex, smooth or creamy and potentially resembling corynebacteria and staphylococci. Mature colonies may be raised and highly convoluted. ^[4]

Cultured: Yes

Functional role:

Importance: Morphologically similar to Actinomyces and Nocardia genus, which contain pathogenic members. ^[3]

Genome structure

Strain: ATCC 17931 ^[5] NCBI RefSeq: NC_014643.1

SIze: 2,506,025 bp

Topology: Circular

Chromosome: 1

Plasmids: 0

Genes:

• Total - 2,126
  • CDS - 2,040
• Protein - 2217
• RNA - 62
  • rRNA - 10
  • tRNA - 49
  • ncRNA - 3

Cell structure and metabolism

Cell wall:

Biofilm formation:

Motility: non-motile, non-sporogenic

Metabolic functions:

Reactions: catalase production, nitrate and nitrite reduction, esculin hydrolysis and acid production from glucose, sucrose, maltose, salicin and glycerol. ^[3]

Ecology

Aerobic ^[4]

Habitat: Oral cavity, teeth, respiratory tract (throat)

Microbe-host interactions:

Pathology

DIsease caused and where:

Application to biotechnology

Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…

Current research

Recent discoveries regarding this species:

References

1. NCBI Taxonomy Browser

2. List of Prokaryotic Names with Standing in Nomenclature

3. Brown, J.M., Georg, L.K., and Waters, L.C. (1969) Laboratory Identification of Rothia dentocariosa and Its Occurrence in Human Clinical Materials. Applied Microbiology 17(1): 150-156.

4. Ferraz, V., McCarthy, K., Smith, D., Koornhof, HJ. (1998) Rothia dentocariosa endocarditis and aortic root abscess. Journal of Infection 37(3): 292-295.

5. Pathosystems Resource Integration Center

6. Salamon, S. A., & Prag, J. (2002) Three cases of Rothia dentocariosa bacteraemia: frequency in Denmark and a review. Scandinavian journal of infectious diseases 34(2): 153-157.

7. Von Graevenitz, A. (2004) Rothia dentocariosa: taxonomy and differential diagnosis. Clinical microbiology and infection 10(5), 399-402.

8. Georg, L. K., & Brown, J. M. (1967) Rothia, gen. nov. an aerobic genus of the family Actinomycetaceae. International Journal of Systematic and Evolutionary Microbiology 17(1), 79-88.

9. Binder, D., Widmer, U., Opravil, M., Krause, M., & Zbinden, R. (1997) Native and prosthetic valve endocarditis caused by Rothia dentocariosa: Diagnostic and therapeutic considerations. Infection 25(1), 22-26.

10. Stackebrandt, E., Rainey, F. A., & Ward-Rainey, N. L. (1997) Proposal for a new hierarchic classification system, Actinobacteria classis nov. International Journal of Systematic and Evolutionary Microbiology 47(2), 479-491.

This page is written by Alexandria Chin for the MICR3004 course, Semester 2, 2016

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