Canine influenza
Classification
Domain; Bacteria Phylum; Negarnaviricota Class; Insthoviricetes Order; Articulavirales family; Orthomyxoviridae [Others may be used. Use NCBI link to find]
Species
NCBI: [1] |
Genus species
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important. Enters organism through inhalation and embeds in the respiratory mucosa, effecting the upper and lower respiratory tract. Virus attaches to epithelial cells due to the binding of the hemagglutinin spike protein to the N-acetylneuraminic acid receptor. Virus then invades cell by endocytosis into the cell cytoplasm, where new virions are replicated and released back into the respiratory tract. The viruses spreads through the trachea within 4 days of exposure and causes swelling, necrosis, flaking of skin, and bone deterioration.
Genome Structure
Single stranded negative sense RNA, 8 chromosomes, circular,
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
Author
Page authored by _____, student of Prof. Bradley Tolar at UNC Wilmington.