User:Newman5

The Cause of Gastric Cancer and Chron's Disease

Artisic drawing of Helicobacter pylori, depicting its rod shape with multiple flagella that enable its fast movement. Photo credit: [1]

By Alexis Newman

Helicobacter pylori is a gram-negative, flagella-bearing spiral-shaped proteobacterium¹ that can grow in extremely acidic environments, like the stomach². Its "Helico-" name derives from its helical body and because of its shape, the bacteria can make its way through the viscous lining of the stomach with help from stomach enzymes. However, once H. pylori gets colonized in the stomach, its shape can convert from the rod shape to an inactive coccoid shape³.

Helicobacter pylori is a class 1 carcinogenic bacteria, 1 being named the most carcinogenic a microbe can be and 4 being non-carcinogenic. H. pylori was determined to be a class 1 carcinogen more than 30 years ago from purely epidemiological data. This investigation showed a positive relationship between gastritis cancer and H. pylori. A couple of years after this phenomenon, in 1991, further evidence showed the prevalence of H. pylori antibodies in patients with gastric and bowel cancer ⁴.

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Legend/credit: Magnified 20,000X, this colorized scanning electron micrograph (SEM) depicts a grouping of methicillin resistant Staphylococcus aureus (MRSA) bacteria. Photo credit: CDC. Every image requires a link to the source.
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