Taenia solium’s Neurological Effect on Epilepsy in Developing Countries

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Scolex (head) of Taenia solium. By Roberto J. Galindo. [https://en.wikipedia.org/wiki/Taenia_solium.


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Taenia solium (also known as an adult tapeworm) is a zoonotic parasite that is responsible for taeniasis and cysticercosis. T. solium is a member of the Taeniidae family that belongs to cyclophyllid cestodes. Neurocysticercosis is the most common parasite infection of the brain and the leading culprit of epilepsy in the developing world. It is most prevalent in Latin America, most of Asia, sub-Saharan Africa, and parts of Oceania, and is the greatest cause of acquired epilepsy worldwide [3]. My question is to investigate what has made this infection a neglected parasite infection in the USA but also the leading cause of onset epilepsy worldwide by looking at developing countries.
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  1. ↑ Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  2. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2017, Kenyon College.

[1] [2] [3] [4] [5]

  1. ↑ [DeGiorgio, C., Medina, M., Duron, R., Zee, C. and Escueta, S. (2004). "Neurocysticercosis". Epilepsy Currents, 4(3), pp.107-111.]
  2. ↑ [En.wikipedia.org. (2017). Taenia solium. [online] Available at: https://en.wikipedia.org/wiki/Taenia_solium.]
  3. ↑ [García, H., Gonzalez, A., Evans, C. and Gilman, R. (2003). Taenia solium cysticercosis. The Lancet, 362(9383), pp.547-556.]
  4. ↑ [Pal, D. (2000). Neurocysticercosis and epilepsy in developing countries. Journal of Neurology, Neurosurgery & Psychiatry, 68(2), pp.137-143.]
  5. ↑ [Rajshekhar, V., Joshi, D., Doanh, N., van De, N. and Xiaonong, Z. (2003). Taenia solium taeniosis/cysticercosis in Asia: epidemiology, impact and issues. Acta Tropica, 87(1), pp.53-60.]
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