A Review of Guillain-Barre Syndrome

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Introduction

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Guillain-Barré syndrome is a rare autoimmune disorder characterized by neuropathy. Some of the symptoms of this disorder are weakness in legs, unsteady walking, feeling achy, shooting pain, high pulse, and labored breathing. Guillain-Barré syndrome has many different causes, and the majority of them are bacterial or viral in nature. Campylobacter, influenza virus, cytomegalovirus, Epstein-Barr virus, Zika virus, Hepatitis A/B/C/E, HIV, mycoplasma pneumonia, surgery, Hodgkin’s lymphoma, vaccinations (very rarely), and COVID-19 infections are all known to trigger the syndrome[1]. Although these can trigger Guillain-Barré syndrome, the actual underlying cause of this disorder is unknown. It does not spread between people and it is not a heritable illness[2].
There are four main types of Guillain-Barré syndrome: acute inflammatory demyelinating polyradiculoneuropathy, Miller Fisher syndrome, acute motor axonal neuropathy, and acute motor-sensory axonal neuropathy[1].

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Conclusion

References

  1. ↑ 1.0 1.1 https://www.mayoclinic.org/diseases-conditions/guillain-barre-syndrome/symptoms-causes/syc-20362793
  2. ↑ https://www.nhs.uk/conditions/guillain-barre-syndrome/causes/
  3. ↑ 3.0 3.1 Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  4. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2021, Kenyon College.

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