Bordetella pertussis and the Importance of Vaccination

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Introduction and History

This illustration depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. The photo credit for this image belongs to Alissa Eckert, who is a medical illustrator at the CDC.


By Alexandra White

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Vaccination is a widely used practice to help prevent infectious disease and commonly spread illnesses. A widely known and common vaccine is used to prevent infection of Bordetella pertussis, the causative agent of Whooping cough. Whooping cough is known as one of the most common infectious disease deaths in the world[1]. The disease results in over 50 million cases worldwide per year, with the majority being unvaccinated individuals present in Third World CountriesCite error: Closing </ref> missing for <ref> tag

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Bordetella pertussis and Infection Stages

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This illustration depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. The photo credit for this image belongs to Alissa Eckert, who is a medical illustrator at the CDC.

B. Pertussis Vaccine History

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Vaccine Virulence

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Why Vaccination?

This graph shows the reported B. pertussis incidences for 1990-2019 by age group (per 100,00 persons). The graph shows infants less than one year old have the greatest risk for disease compared to all other age groups. [https://www.cdc.gov/pertussis/surv-reporting.html

Conclusion

References

  1. ↑ Kerr, J.R. and Matthews, R.C."Bordetella pertussis Infection: Pathogenesis, Diagnosis, Management, and the Role of Protective Immunity." 2000. European Journal of Clinical Microbiology and Infectious Disease 19:77-88.
  2. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named aa



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2022, Kenyon College

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