Small Intestinal Bacterial Overgrowth

From MicrobeWiki, the student-edited microbiology resource

Overview

Small intestinal bacterial overgrowth (SIBO) is defined as the abnormal increase in the overall bacterial population in the small intestine. [1] Common symptoms of SIBO include diarrhea, flatulence, abdominal pain and bloating. [2] [3]Currently there is no single valid test for SIBO, but common ways of screening for SIBO include small-bowel aspiration and quantitative culture and breath testing. [4]

SIBO was first suggested by Barker and Hummel in their 1939 publication “Macrocytic anemia in association with intestinal strictures and anastomoses.”, providing key findings for both the study of Macrocytic anemia and the study of SIBO. [5]





The hypothesis of SIBO and potential detrimental outcomes relevant to children in low-income countries.[1].


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Testing for SIBO

Medical Management of SIBO

Unfortunately, the current management of SIBO is unclear. [6] Common management strategies include using antibiotics

Research also proposes dietary changes to help relieve the functional gastrointestinal (GI) symptoms. [7] Reduce intake of FODMAPs (fermentable oligo-, di-, and mono-saccharides and polyols)—poorly absorbed short-chain carbohydrates can effectively reduce bloating and other functional gastrointestinal symptoms. [7] Other food sources of functional gastrointestinal symptoms including gluten and natural and added food chemicals such as amines and glutamates and the benefit of dietary strategies that reduce the intake of these chemicals are still being researched. [7]

Interactions Between SIBO and Other Systemic Conditions

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Conclusion

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References


Edited by Yufan Lu, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2022, Kenyon College.