Allobaculum fili

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Classification

Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales; Erysipelotrichaceae; Allobaculum

Species

NCBI: [1]

Firmicutes

Description and Significance

Allobaculum fili are rod-shaped cells with tapered ends. These bacteria are found within the gastrointestinal tracts of humans with ulcerative colitis and inflammatory bowel disease. They average about ~1-2 µm in length and ~.7 µm in width. It grows in long chains. The chains of bacteria are in anoxic conditions in temperatures ranging from 30°C to 42°C. This bacteria is significant because we can learn more about what causes inflammatory bowl disease and what specific microbes cause damage.

Genome Structure

Genome sequencing of Allobaculum fili was obtained by using Illumina MiSeq sequencing. The strain was isolated from a patient's intestinal tract with ulcerative colitis. The genome size of the strain is 2580362 base pairs. The G+C content is 50.5 mol%.

Cell Structure, Metabolism and Life Cycle

The structure is rod-shaped with tapered ends as stated above. The cells are gram positive. They are non-motile and show no fimbriae. They have no visible flagella. The optimal pH growth is 6.5-7.0. The strand produces indole and reduces nitrate. After observing the microbe, the researchers found positive reactions in acid phosphatase activity as the method of gaining energy.

Ecology and Pathogenesis

The genus Allobacalum grow in the gut of animals. The known hosts are humans, dogs, mice, and rats. This bacteria has been identified in the context of dietary interventions, aging, and intestinal inflammation. The samples observed for this research were taken from fecael samples of patients with ulcerative colitis and inflammatory bowel disease.

References

Van Muijlwjik, G.H., Rice, T.A., Flavell, R.A., Palm, N.W., de Zoete, M.R. “Allobaculum mucilyticum sp. nov. and Allobaculum fili sp. nov., isolated from the human intestinal tract”. International Journal of Systematic and Evolutionary Microbiology. 2023. Volume 73, Issue 1.

Author

Page authored by Julia Grzeskiewicz, student of Prof. Bradley Tolar at UNC Wilmington.