Parvovirus B19

From MicrobeWiki, the student-edited microbiology resource

Background

The life cycle of Canine Parvovirus. Photo credit: [1]

By Grace Potter

Parvovirus B19 is the only member of the Parvoviridae family that has been found to infect human hosts.[1] It was discovered in 1974, when a research group looking at hepatitis B surface antigens found a serum sample with unexpected results.[1] Another lab in Japan described a similar virus in 1979 that they called "Nakatami".[1] When compared, the two were found to be identical.[1]

In 1985 this virus was officially recognized as a member of the Parvoviridae family due to its similarities in genome size and density.[1]

Section 1

Include some current research, with at least one figure showing data.

Parvoviridae

Genome Structure

The Parvovirus genome is a single strand of DNA with 5,596 nucleotides, 4,830 of which are coding regions.[1] This region contains 2 large open reading frames.[1] One large non-structural protein is coded by one open reading frame, and the second reading frame codes for 2 capsid proteins.[1]

Section 3

Include some current research, with at least one figure showing data.

Section 4

Conclusion

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Cite error: Invalid <ref> tag; no text was provided for refs named ncbi



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski,at Kenyon College,2024