Tectiviridae

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Legend. Image credit: Name or Publication.

Classification

Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes; Kalamavirales; Tectiviridae; Alphatectivirus; Alphatectivirus PRD1

Species

NCBI: [1]

Enterobacteria phage PRD1

Description and Significance

Describe the appearance, habitat, etc. of the organism, and why you think it is important.

Genome Structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?

Single molecule of linear dsDNA that is around 15kbp, its entire sequence is known. The 5' ends of the DNA have covalently linked proteins. It also has inverted terminal repeats at both ends of the DNA sequence which serve as origins of replication.

Cell Structure, Metabolism and Life Cycle

Interesting features of cell structure; how it gains energy; what important molecules it produces.

Viruses like Alphatectivirus PRD1 do not have their own metabolism and are non-living entities that are unable to generate ATP and translate it to form proteins. Instead, Alphatectivirus PRD1 relies on the metabolism of host cells to provide energy and metabolic substances for their life cycles. It is icosahedral in shape, has no external envelope but does have a capsid along with spike proteins. It also has an inner membrane vesicle enclosed by the capsid that is made up of virus encoded proteins and lipids from the host cells plasma membrane.

Ecology and Pathogenesis

Habitat; symbiosis; biogeochemical significance; contributions to environment.

If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

References

https://www.sciencedirect.com/topics/immunology-and-microbiology/enterobacteria-phage-prd1#:~:text=The%20capsid%20of%20Enterobacteria%20phage,are%20used%20for%20receptor%20recognition. https://blog.addgene.org/viral-vectors-101-inverted-terminal-repeats

Author

Page authored by Lee Hinson, Abi Miller, Mariella Dagdag, & Alexis Grimes, students of Prof. Bradley Tolar at UNC Wilmington.