Orthopoxvirus monkeypox

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Legend. Image credit: Name or Publication.

Classification

Domain; Phylum; Class; Order; family [Others may be used. Use NCBI link to find]

Species

NCBI: [1]

Genus species

Description and Significance

Describe the appearance, habitat, etc. of the organism, and why you think it is important.

Genome Structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?

Cell Structure, Metabolism and Life Cycle

Interesting features of cell structure; how it gains energy; what important molecules it produces.

Metabolism

The Monkeypox virus is an obligate intracellular parasite, meaning it cannot carry out metabolic processes independently and is entirely dependent on the host cell's metabolism. The monkeypox virus can hijack and alter the host cell's metabolism, inducing glycolysis in the host cell to provide rapid ATP production and suppressing the host's immune response, all to aid in efficient viral reproduction. 

Ecology and Pathogenesis

Habitat; symbiosis; biogeochemical significance; contributions to environment.

If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Author

Page authored by _____, _____, _____, & _____, students of Prof. Bradley Tolar at UNC Wilmington.