Citrobacter freundii
A Microbial Biorealm page on the genus Citrobacter freundii
Classification
Higher order taxa
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Citrobacter
Domain; Phylum; Class; Order; Family[Others may be used. Use NCBI link to find]
Species
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NCBI: Taxonomy |
Citrobacter Freundii
Description and significance
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.
The Citrobacter species, including Citrobacter Freundii, are aerobic gram-negative bacilli commonly found in water, soil, food, and the intestinal tracts of animals and humans. Citrobacter Feundii is a rod-shaped bacteria, and is typically 1-5 μm in length. Most have many flagella used to move about, but a few are non-motile. It belongs to the family of Enterobacteriaceae. As an opportunistic Pathogens, it is often the cause of significant opportunistic infections, meaning that it does not generally cause disease in healthy, uncompromised human hosts. Otherwise, C. Freundii is known to cause a wide variety of nosocomial infections of the respiratory tract, urinary tract, blood and several other normally sterile sites. It habitat includes the enivronment (soil, water, sewage) and the intestines of mammals. The Citrobacter genus was originally prosped in 1932 by Werkman and Gillen. (Wanf JT) Cultures of C. freundii were isolated and identified in the same year, since then it has been reported to cause a variety of infections in aged, immunocompromised, and debilited patient. C. Freundii has many different imortatn strains in its genome, all of which can cause a different kind of infection. Therefore, one of the main reason te genome of its strains where sequences was in order to find antibiotics that would kill the C. Freundii microbe.
Genome structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
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Ecology
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Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
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References
Edited by student of Rachel Larsen
