Cryptosporidium parvum
A Microbial Biorealm page on the genus Cryptosporidium parvum
Classification
Higher order taxa
Eukaryota; Alveolata; Apicomplexa; Coccidia; Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium; Cryptosporidium parvum
Species
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NCBI: Taxonomy |
Cryptosporidium parvum
Description and significance
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.
Genome structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
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Ecology
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Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
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References
Pain, A., Crossman, L., and Parkhill, J. “Comparative Apicomplexan genomics”. Nature Reviews Microbiology. 2005. Volume 3. p. 454-455. http://www.nature.com/nrmicro/journal/v3/n6/full/nrmicro1174_fs.html
Abrahamsen, M., Templeton, T., Enomoto, S., Abrahante, J., Zhu, G., Lancto, C., Deng, M., Liu, C., Widmer, G., Tzipori, S., Buck, G., Xu, P., Bankier, A., Dear, P., Konfortov, B., Spriggs, H., Lyer, L., Anantharaman, V., Aravind, L., and Kapur, V. “Complete Genome Sequence of the Apicomplexan, Cryptosporidium parvum”. Science. 2004. Volume 304. p. 441-445. http://www.sciencemag.org/cgi/content/full/304/5669/441
Rider, S., Cai, X., Sullivan, W., Smith, A., Radke, J., White, M., and Zhu, G. “The Protozoan Parasite Cryptosporidium parvum Possesses Two Functionally and Evolutionarily Divergent Replication Protein A Large Subunits”. J. Biol. Chem. 2005. Volume 280. p. 31460-31469. http://www.jbc.org/cgi/content/full/280/36/31460
Casadevall, A., Dadachova, E., Pirofski, L. “Passive Antibody Therapy for Infectious Diseases”. Nature Reviews Microbiology. 2004. Volume 2. p. 695-703 http://www.nature.com/nrmicro/journal/v2/n9/full/nrmicro974_fs.html
Pain, A., Crossman, L., Sebaihia, M., Cerdeño-Tárraga, A., and Parkhill, J. “Strength in Diversity”. Nature Reviews Microbiology. 2004. Volume 2. p. 358-359. http://www.nature.com/nrmicro/journal/v2/n5/full/nrmicro889_fs.html
Widmer, G., Yang, Y., Bonilla, R., Tanriverdi, S., and Ciociola, K. “Preferential infection of dividing cells by Cryptosporidium parvum”. Parasitology. 2006. Volume 133. p. 131-138. http://journals.cambridge.org/action/displayFulltext?type=6&fid=454979&jid=&volumeId=&issueId=02&aid=454977&fulltextType=RA&fileId=S0031182006000151
“Cryptosporidiosis Control and Prevention”. Center for Disease Control and Prevention. http://www.cdc.gov/ncidod/dpd/parasites/cryptosporidiosis/crypto_control_prevent.htm
Bandyopadhyay, K., Kella, K., Moura, I., Cristina, M., Carollo, C., Graczyk, T., Slemenda, S., ohnston, S., Silva, A. “A rapid microsphere assay for identification of Cryptosporidium hominis and Cryptosporidium parvum in stool and environmental samples”. 2007. Published online ahead of print. http://jcm.asm.org/cgi/reprint/JCM.00138-07v1?view=long&pmid=17652477
"Foodborne Pathogenic Microorganisms and Natural Toxins Handbook, Cryptosporidium parvum”. U.S. Food and Drug Administration. http://www.cfsan.fda.gov/~mow/chap24.html
Guisar R., Herrera, M., Bandala, E., Garcia, J., and Corona-Vasquez, B. “Inactivation of waterborne pathogens using solar photocatalysis”. Journal of Advanced Oxidation Technologies. 2007. Volume 10. p. 435-438. http://portal.isiknowledge.com/portal.cgi?DestApp=WOS&Func=Frame
Edited by student of Rachel Larsen Angela Wang
