Foot-and-Mouth Disease

Livestock is affected by Foot and Mouth Disease; cows, pigs, sheep and llamas. [1].

Baltimore Classification

Group IV. Positive single-stranded RNA (picornavirus)

Higher order categories

Order Picrnovirales
Family Picornaviridae
Genus Aphthovirus
Species Bovine rhinitis virus

Description and Significance

This aphthovirus can survive a range of conditions outside of a host cell. It can persist in below-freezing temperatures as well as through the high temperatures of pasteurization, making the eradication of this virus in a cattle population and throughout its byproducts very difficult. Herds are quickly affected to FMD due to their close contact with each other and materials that carry the virus. Cloven-hoofed livestock such as cows, pigs, sheep, goats, and sometimes llama and aplaca herds are the most often affected animals. Outbreaks of FMD have not occurred in the United States since the late 1920's but Asia, Africa, and regions in the Middle East still suffer.
It's highly contagious nature as well as it's relation to the human-affecting enterovirus that causes hand, foot, and mouth disease make it a model virus to study. If infected animals come into contact with wild herds, deer and buffalo will also become diseased and sources of food and ecological balance will be rendered dangerous.

Viral Ecology & Pathology

Infected animals can carry the virus prior to showing symptoms and for up to four years afterwards [1]. The virus spreads easily through contact, air transmission, and can survive on the ground an on other materials, such as feed. The virus spread when cutaneous blisters, known as vesicles, rupture and fluid containing virions is released.

References

Example: Weir, Jerry P. " Genomic Organization and Evolution of the Human Herpesviruses." Virus Genes 16.1 (1998): 85-93.

Page authored for BIOL 375 Virology, September 2012