Herpesviridae: Viral Cycle, Capsid Transport, and Cancer Treatment
From MicrobeWiki, the student-edited microbiology resource
Introduction
![](/images/thumb/d/d0/Herpes_simplex_virions%2C_TEM.jpg/300px-Herpes_simplex_virions%2C_TEM.jpg)
Transmission electron micrograph of herpes simplex virus. Some nucleocapsids are empty, as shown by penetration of electron-dense stain. http://phil.cdc.gov/PHIL_Images/08301998/00014/B82-0474_lores.jpg
By Michael Gallaher
Pathology
Include some current research, with at least one figure showing data.
Cell Cycle
Include some current research, with at least one figure showing data.
![](/images/thumb/f/ff/UL6_portal_Cryo-EM.jpg/300px-UL6_portal_Cryo-EM.jpg)
Cryo-EM tomograpgy of the capsid portal formed by a 12-mer of the UL6 protein. The portal forms at a vertex of the capsid. Cardone et al, 2007. http://www.sciencedirect.com/science/article/pii/S004268220600804X
![](/images/thumb/7/77/HSV_virion_assembly.jpg/300px-HSV_virion_assembly.jpg)
Diagram of HSV virion assembly. After exiting the nucleus, secondary envelope formation occurs at two separate sites, and is then later joined together. Mettenleiter et al, 2006. http://www.sciencedirect.com/science/article/pii/S1369527406000968
Section 3
Include some current research, with at least one figure showing data.
Conclusion
Overall text length at least 3,000 words, with at least 3 figures.
References
Edited by student of Joan Slonczewski for BIOL 238 Microbiology, 2011, Kenyon College.