Bacteroides finegoldii

From MicrobeWiki, the student-edited microbiology resource
This student page has not been curated.

Classification

Higher order taxa

Bacteria; Bacteroidetes (phylum); Bacteroidetes (class); Bacteroidales (order); Bacteroidaceae (family); Bacteroides (genus)

Species

Bacteroides finegoldii

Relatedness to other species in the Bacteroides genus

16S rRNA gene sequence similarities show that B. finegoldii's closest neighbors are Bacteroides thetaiotaomicron and Bacteroides ovatus.

Characteristics

General Background

Bacteroides finegoldii is a strictly anaerobic, Gram-negative rod bacteria that occurs in human feces.

Morphology

Bacteroides finegoldii is non-spore-forming, non-motile, Gram-negative rod bacteria, about 0.80 µm wide and 1.5-4.5 µm long and occuring singly.

Molecular structure

The major fatty acids are anteiso-C15:0 (31.8–36.2%) and iso- C17:0 3-OH (13.1–14.5%). The DNA G+C content is 42.4–43.0 mol%.

Metabolism

The optimum temperature for growth is about 37 C. B. finegoldii produces acid from the metabolism of glucose, lactose, sucrose, maltose, salicin, xylose, arabinose, cellobiose, mannose, raffinose and rhamnose. The bacteria grows in the presence of bile.

Current Research

As Bacteroides finegoldii is found in the feces of humans, it has been the subject of several recent research projects investigating the stool microbome and metabolome. Specifically, research is trying to differentiate between the stool microbiome and metabolome of colorectal cancer patients and healthy adults as well as identifying the microbes involved in inflammatory bowel disease in children and young adults.

References

Bakir, M., Kitahara, M., Sakamato, M., Matsumoto, M., and Benno, Y. "Bacteroides finegoldii gen. nov., sp. nov., isolated from human faeces". International Journal of Systematic and Evolutionary Microbiology. 2006. Volume 56. p. 931–935.

Weir, T., Manter, K., Sheflin, A., Barnett, A., and Heuberger, A. "Stool Microbiome and Metabolome Differences between Colorectal Cancer Patients and Healthy Adults". PloS One. 2013. Volume 8. p. 70803.

Zitomersky, N., Atkinson, B., Franklin, S., Mitchell, P., Snapper, S., Comstock, L., and Bousvaros, A. "Characterization of adherent bacteroidales from intestinal biopsies of children and young adults with inflammatory bowel disease". PloS One. 2013. Volume 8. p. 63686.

Edited by (Jenna Lane), student of Rachel Larsen at the University of Southern Maine