Bacteroides fragilis: Difference between revisions

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==Classification==
Kingdom: Bacteria<br>
Phylum: Bacteroidetes<br>
Class: Bacteroidia<br>
Order: Bacteroidales<br>
Family: Bacteroidaceae<br>
Genus: Bacteroides<br>
Species: <i>Bacteroides fragilis</i><br>


==Introduction==
==Introduction==
<i>Bacteroides fragilis</i> (BF) is a Gram-negative bacterium found in the human colon [[#References|[1]]]. It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality [[#References|[2]]]. In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. [[#References|[3]]] This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.<br><br>
<i>Bacteroides fragilis</i> (BF) is a Gram-negative bacterium found in the human colon [[#References|[1]]]. Although it is relatively rare compared to other species of <i>Bacteroides</i>, it is the most common clinical isolate [[#References|[2]]]. BF is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality [[#References|[2]]]. In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. [[#References|[3]]] This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.<br><br>




[[Image:Bacteroides_fragilis.jpg|thumb|300px|right|Colony of <i>Bacteroides fragilis</i>, Gram-stained and magnified 1000x.  Image taken by Don Stalon. Source: [https://phil.cdc.gov/Details.aspx?pid=11198 Centers for Disease Control and Prevention]]]
[[Image:Bacteroides_fragilis.jpg|thumb|300px|right|Colony of <i>Bacteroides fragilis</i>, Gram-stained and magnified 1000x.  Image taken by Don Stalon. Source: [https://phil.cdc.gov/Details.aspx?pid=11198 Centers for Disease Control and Prevention]]]
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<br><b>Legend/credit:</b> Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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==Section 1 Genetics==
==Genetics==
Include some current research, with at least one image.<br><br>
Include some current research, with at least one image.<br><br>


Sample citations: <ref>[http://www.plosbiology.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pbio.1000005&representation=PDF Hodgkin, J. and Partridge, F.A. "<i>Caenorhabditis elegans</i> meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847443/ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.]</ref>
<br><br>A citation code consists of a hyperlinked reference within "ref" begin and end codes.


==Section 2 Microbiome==
==Section 2 Microbiome==
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==References==
==References==
[1] Kuwahara, Tomomi, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.<br><br>
<ref>[https://www.pnas.org/content/101/41/14919.short Kuwahara, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.]</ref><br><br>
 
<ref>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522005/ Salyers, A. A. (1984) Annu. Rev. Microbiol. 38, 293-313.]</ref><br><br>


[2] Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.<br><br>
<ref>[https://academic.oup.com/cid/article-abstract/20/6/1492/477370 Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.]</ref><br><br>


[3] Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.<br><br>
<ref>[https://www.ncbi.nlm.nih.gov/pubmed/19366918 Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.]</ref><br><br>


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Revision as of 18:15, 1 December 2019

This student page has not been curated.

Classification

Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides fragilis

Introduction

Bacteroides fragilis (BF) is a Gram-negative bacterium found in the human colon [1]. Although it is relatively rare compared to other species of Bacteroides, it is the most common clinical isolate [2]. BF is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality [2]. In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. [3] This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.


Colony of Bacteroides fragilis, Gram-stained and magnified 1000x. Image taken by Don Stalon. Source: Centers for Disease Control and Prevention



Genetics

Include some current research, with at least one image.


Section 2 Microbiome

Include some current research, with a second image.

Conclusion

Overall text length should be at least 1,000 words (before counting references), with at least 2 images. Include at least 5 references under Reference section.


References

[1]

[2]

[3]

[4]


Edited by James Cawthon, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.