Blautia Hydrogenotrophica: Difference between revisions
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==Genome Structure== | ==Genome Structure== | ||
''Blautia Hydrogenotrophica'' strain DSM 10507 | ''Blautia Hydrogenotrophica'' strain DSM 10507 contains 3,565,428 base pairs (NCBI, 2011). The G+C content of the DNA is 45.2 mol% (Bernalier et al. 1996). | ||
Through in silico analysis of the ''Blautia hydrogenotrophica'' genome, it was found that all of the genes involved in the Wood-Ljungdahl pathway were present. This includes eight genes that are thought to encode subunits of iron-only hydrogenases. (Bain, 2010) | |||
==Cell Structure, Metabolism and Life Cycle== | ==Cell Structure, Metabolism and Life Cycle== | ||
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The Blautia hydrogenotrophica is gram-positive, non-sporulating, coccobacillus shaped bacterium with an average size of 0.7-0.6 mm. Through the use of negatively stained cells, it can be observed that the organism lacks flagella. (Bernalier et al. 1996) | The Blautia hydrogenotrophica is gram-positive, non-sporulating, coccobacillus shaped bacterium with an average size of 0.7-0.6 mm. Through the use of negatively stained cells, it can be observed that the organism lacks flagella. (Bernalier et al. 1996) | ||
Hydrogenotrophica, meaning feeds on hydrogen, refers to the organism’s ability to use H2/CO2 as energy source for | Hydrogenotrophica, meaning feeds on hydrogen, refers to the organism’s ability to use H2/CO2 as energy source for growth (Liu et al., 2008). | ||
Revision as of 00:38, 24 April 2011
Classification
Bacteria; Firmicutes; Clostridia; Clostridiales; Blautia
Species
Blautia hydrogenotrophica, formerly known as Ruminococcus hydrogenotrophicus
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NCBI: Taxonomy |
Description and Significance
Genome Structure
Blautia Hydrogenotrophica strain DSM 10507 contains 3,565,428 base pairs (NCBI, 2011). The G+C content of the DNA is 45.2 mol% (Bernalier et al. 1996).
Through in silico analysis of the Blautia hydrogenotrophica genome, it was found that all of the genes involved in the Wood-Ljungdahl pathway were present. This includes eight genes that are thought to encode subunits of iron-only hydrogenases. (Bain, 2010)
Cell Structure, Metabolism and Life Cycle
The Blautia hydrogenotrophica is gram-positive, non-sporulating, coccobacillus shaped bacterium with an average size of 0.7-0.6 mm. Through the use of negatively stained cells, it can be observed that the organism lacks flagella. (Bernalier et al. 1996)
Hydrogenotrophica, meaning feeds on hydrogen, refers to the organism’s ability to use H2/CO2 as energy source for growth (Liu et al., 2008).
Ecology and Pathogenesis
References
Bain, J., Faith, J., Gordon, J., Muehlbauer, M., Newgard, C., Rey, F., and Stevens, R. “Dissecting the in Vivo Metabolic Potential of Two Human Gut Acetogens.” Journal of Biological Chemistry, 2010. Volume 285. P. 22082-22090. Accessed April 18, 2011. <http://www.jbc.org/content/285/29/22082.full>
Bernalier, A., Collins, MD., Leclerc, M., Rochet, V., Willems, A. “Ruminococcus hydrogenotrophicus sp. nov., a new H2/CO2-utilizing acetogenic bacterium isolated from human feces.” Archives of Microbiology, 1996. Volume 166(3). p. 176-83. Accessed April 16, 2011. < http://www.springerlink.com/content/tt7hew38ngt4j9d7/>
Liu, C., Finegold, S., Song, Y., and Lawson, P. “Reclassification of Clostridium coccoides, Ruminococcus hansenii, Ruminococcus hydrogenotrophicus, Ruminococcus luti, Ruminococcus productus and Ruminococcus schinkii as Blautia coccoides gen. nov., comb. nov., Blautia hansenii comb. nov., Blautia hydrogenotrophica comb. nov., Blautia luti comb. nov., Blautia producta comb. nov., Blautia schinkii comb. nov. and description of Blautia wexlerae sp. nov., isolated from human faeces.” International Journal of Systematic and Evollutionary Microbiology, 2008. Volume 58. p. 1896-1902. Accessed April 21, 2011. <http://ijs.sgmjournals.org/cgi/content/full/58/8/1896>
NCBI (National Center for Biotechnology Information). “Blautia hydrogenotrophica DSM 10507, whole genome shotgun sequence.” Accessed April 21, 2011. <http://www.ncbi.nlm.nih.gov/nuccore/NZ_ACBZ00000000>
Author
Page authored by Megan Buhl and Blaze Budd, students of Prof. Jay Lennon at Michigan State University.
