Borrelia burgdorferi and Lyme Disease Detection: Difference between revisions
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==Overview== | ==Overview== | ||
Borrelia burgdorferi is a bacterial eubacterial phylum spirochaete and a tick borne parasite. It is one of the known causative agents for Lyme Disease. Borrelia burgdorferi was named after Willy Burgdorfer who first isolated the bacteria in 1982. The spirochete is a flat wave shape that is commonly 0.3 micrometers in width and ranges from 5 to 20 micrometers in length. It has both an outer and inner membrane with a thin layer of peptidoglycan separating the membranes. Seven to eleven bundled periplasmic flagella reside within the membranes and allow the bacterium to move through a highly viscosity medium, which increases its virulence factor. The flagellar filaments wrap around the cell and rotate in order to help the flagellar motor propel the bacteria in a signature corkscrew motion. The doubling time of the bacteria ranges from 24 to 48 hours. Borrelia burgdorferi is different from common pathogenic bacteria because it lacks the common virulence factors like toxins, a specialized secretion system, and lipopolysaccharides. The bacteria lacks common biosynthetic abilities and heavily relies on its host for nutrients and other factors for its survival. | |||
[[Image:PHIL_22882_lores.jpg|thumb|300px|right|This illustration depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. The photo credit for this image belongs to Alissa Eckert, who is a medical illustrator at the [http://www.cdc.gov/ CDC].]] | [[Image:PHIL_22882_lores.jpg|thumb|300px|right|This illustration depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. The photo credit for this image belongs to Alissa Eckert, who is a medical illustrator at the [http://www.cdc.gov/ CDC].]] | ||
<br>By Roya Best<br> | <br>By Roya Best<br> | ||
Revision as of 03:59, 18 April 2022
Overview
Borrelia burgdorferi is a bacterial eubacterial phylum spirochaete and a tick borne parasite. It is one of the known causative agents for Lyme Disease. Borrelia burgdorferi was named after Willy Burgdorfer who first isolated the bacteria in 1982. The spirochete is a flat wave shape that is commonly 0.3 micrometers in width and ranges from 5 to 20 micrometers in length. It has both an outer and inner membrane with a thin layer of peptidoglycan separating the membranes. Seven to eleven bundled periplasmic flagella reside within the membranes and allow the bacterium to move through a highly viscosity medium, which increases its virulence factor. The flagellar filaments wrap around the cell and rotate in order to help the flagellar motor propel the bacteria in a signature corkscrew motion. The doubling time of the bacteria ranges from 24 to 48 hours. Borrelia burgdorferi is different from common pathogenic bacteria because it lacks the common virulence factors like toxins, a specialized secretion system, and lipopolysaccharides. The bacteria lacks common biosynthetic abilities and heavily relies on its host for nutrients and other factors for its survival.
By Roya Best
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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC. Every image requires a link to the source.
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Lyme Disease- Overview
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Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2022, Kenyon College
