Campylobacter coli

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A Microbial Biorealm page on the genus Campylobacter coli

Classification

Higher order taxa

Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter

Species

Campylobacter coli

NCBI: Taxonomy

Description and significance

Campylobacter coli (C.coli) is a specie found in the epsilonproteobacteria class. It is a gram-negative S-shaped curved, somewhat rod-shaped cell, about 0.2-0.5 micrometers long, contains a single polar flagellum at one end, and usually lives in the intestinal tract of animal.[1] The bacteria colonizes the intestinal epithelium to a point that it breaks out from the epithelial layer and spread into the bloodstream.[2] C.coli is very similar to its bacteria relative, campylobacter jejuni (C.jejuni), in which both causes inflammation of the intestine and causes diarrhea in infected animals and human.[1] There has been many studies and research for finding a treament, one of which is the use of antimicrobial chemotherapy for patients with severe infection of this bacteria. Erythromycin, fluoroquinolones, and tetracycline were found to be the best antimicrobial drugs.[4]C.coli strands were isolated usually from pigs, but also from birds and surface water either by classical or molecular methods, including 16S rDNA shotgun sequencing and polymerase chain reactions to differentiate between C.coli and C.jejuni.[3]

Genome structure

C.coli is found to be 1,860,666 nucleotides long and contains 2033 genes, in which 1967 of those are protein coding. It also contains 58 different structures of RNAs.

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology, Pathology, and Application to Biotechnology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Rachel Larsen