Campylobacter fetus: Difference between revisions

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==Genome structure==
==Genome structure==
Campylobacter fetus is a spiral slender, spirally curved bacterial pathogen, enclosed with an S layer of special crystalline surface proteins. (Their unique function will be discussed later) . It is a gram negative species holding two membranes and a thin cell wall in between. Since it is a pathogen, it can reside anywhere in the human body. The campylobacter S layer proteins were found to have a virulence factor in resistance to the host immune defense mechanisms. Two subspecies were then suspected to exist in the campylobacter. One was Campylobacter fetus subsp. fetus and Campylobacter fetus subsp. Venerealis. To further investigate the genetic diversity among C. fetus strains of different origins, multiple genetic analyzing were used such as polymorphic DNA (RAPD), pulsed-field gel electrophoresis (PFGE), and DNA-DNA hybridization. I t was also mainly found that its natural habitat of C. fetus subsp. fetus is the intestinal tract of cattle, but it can also cause abortions.
Campylobacter Fetus was completely sequences and was found to have 1820 genes. It has a circular DNA. Its genome length is 1,773,615 nt.GC content is 33%, coding sequence is 90%.It as 3441 proteins.  
The two stains that were found were dividing based on their lipopolysaccharide (LPS) composition. These unique stains must contain conserved sequences so to check their unique versus mutual sequences we used gel electrophoresis. This helped answer the unique method of this pathogen in changing its S layer proteins.
Different study reported the different multiple somewhat homologous and highly conserved surface layer proteins, tightly packed in this species. They encode for the 97-149 kDa. They attach to the N terminus of the cell wall lipopolysaccharide non covalently.


==Cell structure and metabolism==
==Cell structure and metabolism==

Revision as of 03:50, 27 April 2007

A Microbial Biorealm page on the genus Campylobacter fetus

Classification

Higher order taxa

Bacteria; Proteobacteria; Epsilon Proteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter

Species

C. fetus


NCBI: Taxonomy

Description and significance

Campylobacter fetus is a spiral slender, spirally curved bacterial pathogen, enclosed with an S layer of special crystalline surface proteins. (Their unique function will be discussed later) . It is a gram negative species holding two membranes and a thin cell wall in between. Since it is a pathogen, it can reside anywhere in the human body. The campylobacter S layer proteins were found to have a virulence factor in resistance to the host immune defense mechanisms. Two subspecies were then suspected to exist in the campylobacter. One was Campylobacter fetus subsp. fetus and Campylobacter fetus subsp. Venerealis. To further investigate the genetic diversity among C. fetus strains of different origins, multiple genetic analyzing were used such as polymorphic DNA (RAPD), pulsed-field gel electrophoresis (PFGE), and DNA-DNA hybridization. I t was also mainly found that its natural habitat of C. fetus subsp. fetus is the intestinal tract of cattle, but it can also cause abortions.

Genome structure

Campylobacter Fetus was completely sequences and was found to have 1820 genes. It has a circular DNA. Its genome length is 1,773,615 nt.GC content is 33%, coding sequence is 90%.It as 3441 proteins. The two stains that were found were dividing based on their lipopolysaccharide (LPS) composition. These unique stains must contain conserved sequences so to check their unique versus mutual sequences we used gel electrophoresis. This helped answer the unique method of this pathogen in changing its S layer proteins. Different study reported the different multiple somewhat homologous and highly conserved surface layer proteins, tightly packed in this species. They encode for the 97-149 kDa. They attach to the N terminus of the cell wall lipopolysaccharide non covalently.

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Rachel Larsen and Kit Pogliano