Chlamydophila pecorum: Difference between revisions
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==Pathology== | ==Pathology== | ||
Chlamydophila pecorum is pathogenic and is highly adapted for infection within certain mammalian host. Its mechanism of infecting the host is termed the developmental cycle, which consists of infection, growth, maturation, release and reinfection. They cycle begins with the elementary bodies (EB) attaching into the host cells. The EB are small, rigid particles that are osmotically stable, but metabolically inert and thus unable to grow and divide. They also exist in the extracellular environment until a host cell is available for intracellular growth. After its entry into the host cell, EB converts to reticulate body (RB) that grow and divide by binary fission with the inclusion, which are intracellular, membrane enclosed organelle that help the growth of C.pecorum. RBs are larger, osmotically unstable and unable to attach to the host cell so they are not infectious. RB eventually converts back to infectious EB in order to release EB into the environment and infect other neighboring host cells. | |||
C.pecorum only mammals like cattle, sheep, goats, koalas and swine. In koala, it causes urinary tract disease, infertility, and reproductive diseases. In other mammals, it is associated with abortion, conjunctivitis, encephalomyelitis, pneumonia, polyarthritis and enteritis. Symptoms are either absent or indolent so it is hard to diagnose. There is no evidence yet that C.pecorum can be transmitted from animals to humans. | |||
==Application to Biotechnology== | ==Application to Biotechnology== |
Revision as of 02:32, 29 August 2007
A Microbial Biorealm page on the genus Chlamydophila pecorum
Classification
Higher order taxa
Domain: Bacteria; Phylum: Chlamydiae; Class: Chlamydiales; Order:Chlamydiaceae; Family: Chlamydophila; Genus: Chlamydophila
Species
NCBI: Taxonomy |
Genus species: Chlamydophila pecorum
Description and significance
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.
Genome structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.
Ecology
Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.
Pathology
Chlamydophila pecorum is pathogenic and is highly adapted for infection within certain mammalian host. Its mechanism of infecting the host is termed the developmental cycle, which consists of infection, growth, maturation, release and reinfection. They cycle begins with the elementary bodies (EB) attaching into the host cells. The EB are small, rigid particles that are osmotically stable, but metabolically inert and thus unable to grow and divide. They also exist in the extracellular environment until a host cell is available for intracellular growth. After its entry into the host cell, EB converts to reticulate body (RB) that grow and divide by binary fission with the inclusion, which are intracellular, membrane enclosed organelle that help the growth of C.pecorum. RBs are larger, osmotically unstable and unable to attach to the host cell so they are not infectious. RB eventually converts back to infectious EB in order to release EB into the environment and infect other neighboring host cells.
C.pecorum only mammals like cattle, sheep, goats, koalas and swine. In koala, it causes urinary tract disease, infertility, and reproductive diseases. In other mammals, it is associated with abortion, conjunctivitis, encephalomyelitis, pneumonia, polyarthritis and enteritis. Symptoms are either absent or indolent so it is hard to diagnose. There is no evidence yet that C.pecorum can be transmitted from animals to humans.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
Enter summaries of the most recent research here--at least three required
References
Edited by student of Rachel Larsen