Chlamydophila pneumoniae: Difference between revisions

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==Description and Significance==
==Description and Significance==
'Chlamydophila pneumoniae'' is a species of bacteria that is known to be a major cause of pneumonia in humans. Similar to viruses, ''Chlamydophila pneumoniae'' is a parasitic organism that cannot reproduce outside of the host cell and is thus dependent on the integrity of the host cell for survival.
''Chlamydophila pneumoniae'' is a species of bacteria that is known to be a major cause of pneumonia, bronchitis, and atherosclerosis in humans. Similar to viruses, ''Chlamydophila pneumoniae'' is a parasitic organism that cannot reproduce outside of the host cell and is thus dependent on the integrity of the host cell for survival.


==Genome Structure==
==Genome Structure==
Describe the size and content of the genome. How many chromosomes?  Circular or linear?  Other interesting features?  What is known about its sequence?
The gene sequence of ''Chlamydophila pneumoniae CWL029'', the strain most common in the United States, has been sequenced, as with many others, in 2000. The genome contains 1,230,230 base pairs of circular DNA. Other interesting features?  What is known about its sequence?
Does it have any plasmids?  Are they important to the organism's lifestyle?
Does it have any plasmids?  Are they important to the organism's lifestyle?


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==References==
==References==
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10871362 Shirai, M., Hirakawa, H., Kimoto, M., Tabuchi, M., Kishi, F., Ouchi, K., Shiba, T., Ishii, K., Hattori, M., Kuhara, S., and Nakazawa, T. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Nucleic Acids Res.(2000) 28:2311-2314.]
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10319462 Everett, K.D., Bush, R.M., Andersen, A.A. "Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms." Int. J. Syst. Bacteriol. (1999) 49:415-440..]
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10319462 Everett, K.D., Bush, R.M., Andersen, A.A. "Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms." Int. J. Syst. Bacteriol. (1999) 49:415-440..]


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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8102247 Fukushi, H., and Hirai, K. "Restriction fragment length polymorphisms of rRNA as genetic markers to differentiate Chlamydia spp." Int. J. Syst. Bacteriol. (1993) 43:613-617.]
[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=8102247 Fukushi, H., and Hirai, K. "Restriction fragment length polymorphisms of rRNA as genetic markers to differentiate Chlamydia spp." Int. J. Syst. Bacteriol. (1993) 43:613-617.]


Edited by student of [mailto:ralarsen@ucsd.edu Rachel Larsen] and Kit Pogliano
Edited by student of [mailto:ralarsen@ucsd.edu Rachel Larsen] and Kit Pogliano

Revision as of 16:23, 3 May 2007

A Microbial Biorealm page on the genus Chlamydophila pneumoniae

Classification

Higher order taxa

Kingdom: Bacteria; Phylum: Chlamydiae; Order: Chlamydiales; Genus: Chlamydophila; Species: C. pneumoniae; [NCBI]

Species

NCBI: Taxonomy

Chlamydophila pneumoniae

Description and Significance

Chlamydophila pneumoniae is a species of bacteria that is known to be a major cause of pneumonia, bronchitis, and atherosclerosis in humans. Similar to viruses, Chlamydophila pneumoniae is a parasitic organism that cannot reproduce outside of the host cell and is thus dependent on the integrity of the host cell for survival.

Genome Structure

The gene sequence of Chlamydophila pneumoniae CWL029, the strain most common in the United States, has been sequenced, as with many others, in 2000. The genome contains 1,230,230 base pairs of circular DNA. Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

Shirai, M., Hirakawa, H., Kimoto, M., Tabuchi, M., Kishi, F., Ouchi, K., Shiba, T., Ishii, K., Hattori, M., Kuhara, S., and Nakazawa, T. "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA." Nucleic Acids Res.(2000) 28:2311-2314.

Everett, K.D., Bush, R.M., Andersen, A.A. "Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms." Int. J. Syst. Bacteriol. (1999) 49:415-440..

Gaydos, C.A., Palmer, L., Quinn, T.C., Falkow, S., and Eiden, J.J. "Phylogenetic relationship of Chlamydia pneumoniae to Chlamydia psittaci and Chlamydia trachomatis as determined by analysis of 16S ribosomal DNA sequences." Int. J. Syst. Bacteriol. (1993) 43:610-612.

Fukushi, H., and Hirai, K. "Restriction fragment length polymorphisms of rRNA as genetic markers to differentiate Chlamydia spp." Int. J. Syst. Bacteriol. (1993) 43:613-617.


Edited by student of Rachel Larsen and Kit Pogliano