Effects of Pathogen-Vector Interactions on the Transmission of Dengue Virus

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Viral Replication



Figure ?. DENV (+)ssRNA genome and schematic of virion replication within the host cell.[DHF has link 21



DENV is a positive strand RNA virus, so once it is endocytosed by the host cell and escapes the endosome it can immediately begin translation of its genome. Like other (+)ssRNA viruses it must transcribe a negative strand RNA template to transcribe new copies of its genome.

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