Helicobacter pylori: Difference between revisions
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==Description and significance== | ==Description and significance== | ||
<em>Helicobacter pylori</em> is a Gram negative that has a 'helical' shaped body with 6-8 flagella at one end. <em>H. pylori </em> is found in a very acidic environment, a pH of 2.0 or less. It is commonly found inside the lining of the stomach and duodenum. <em>H. pylori can cause peptic ulcers and gastritis that can lead to gastric cancer and gastric MALT lymphoma (mucosa-associated lyphoid tissue). | |||
By following the Koch's postulates, <em>H. pylori</em> was discovered by Drs. Robin Warren and Barry Marshall in 1983 that this organism was related to peptic ulcers. | |||
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. | Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. | ||
Include a picture or two (with sources) if you can find them. | Include a picture or two (with sources) if you can find them. | ||
Revision as of 06:53, 3 May 2007
A Microbial Biorealm page on the genus Helicobacter pylori
Classification
Higher order taxa
Bacteria (Domain); Proteobacteria (Phylum); Epsilon Proteobacteria (Class); Campylobacterales (Order); Helicobacteraceae (Family); Helicobacter (Genus)
Species
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NCBI: Taxonomy |
Helicobacter pylori
Description and significance
Helicobacter pylori is a Gram negative that has a 'helical' shaped body with 6-8 flagella at one end. H. pylori is found in a very acidic environment, a pH of 2.0 or less. It is commonly found inside the lining of the stomach and duodenum. H. pylori can cause peptic ulcers and gastritis that can lead to gastric cancer and gastric MALT lymphoma (mucosa-associated lyphoid tissue).
By following the Koch's postulates, H. pylori was discovered by Drs. Robin Warren and Barry Marshall in 1983 that this organism was related to peptic ulcers.
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.
Genome structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.
Ecology
Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.
Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
Enter summaries of the most recent research here--at least three required
References
Edited by Katherine Park student of Rachel Larsen and Kit Pogliano
