Herpesviridae: Viral Cycle, Capsid Transport, and Cancer Treatment

Introduction

Transmission electron micrograph of herpes simplex virus. Some nucleocapsids are empty, as shown by penetration of electron-dense stain. http://phil.cdc.gov/PHIL_Images/08301998/00014/B82-0474_lores.jpg

By Michael Gallaher

Pathology

Include some current research, with at least one figure showing data.

Herpes labialis (HSV-1) infection of the upper lip. Original uploader was Bernard bill5 at nl.wikipedia Permission for use: PD-USGOV-HHS-CDC.

Cell Cycle

Include some current research, with at least one figure showing data.

Cryo-EM tomograpgy of the capsid portal formed by a 12-mer of the UL6 protein. The portal forms at a vertex of the capsid.Cardone et al, 2007.

Diagram of HSV virion assembly. After exiting the nucleus, secondary envelope formation occurs at two separate sites, and is then later joined together.Mettenleiter et al, 2006.

Section 3

Include some current research, with at least one figure showing data.

Conclusion

Overall text length at least 3,000 words, with at least 3 figures.

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Joan Slonczewski for BIOL 238 Microbiology, 2011, Kenyon College.