Herpesviridae: Viral Cycle, Capsid Transport, and Cancer Treatment

Introduction

Transmission electron micrograph of herpes simplex virus. Some nucleocapsids are empty, as shown by penetration of electron-dense stain. http://phil.cdc.gov/PHIL_Images/08301998/00014/B82-0474_lores.jpg

By Michael Gallaher

Pathology

Include some current research, with at least one figure showing data.

Herpes labialis (HSV-1) infection of the upper lip. Original uploader was Bernard bill5 at nl.wikipedia Permission for use: PD-USGOV-HHS-CDC.

Cell Cycle

Include some current research, with at least one figure showing data.

Cryo-EM tomograpgy of the capsid portal formed by a 12-mer of the UL6 protein. The portal forms at a vertex of the capsid. Cardone et al, 2007. http://www.sciencedirect.com/science/article/pii/S004268220600804X

Diagram of HSV virion assembly. After exiting the nucleus, secondary envelope formation occurs at two separate sites, and is then later joined together. Mettenleiter et al, 2006. http://www.sciencedirect.com/science/article/pii/S1369527406000968

Section 3

Include some current research, with at least one figure showing data.

Conclusion

Overall text length at least 3,000 words, with at least 3 figures.

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Joan Slonczewski for BIOL 238 Microbiology, 2011, Kenyon College.