Human T-Lymphotropic Virus Type 1: (HTLV-1)

Introduction

This section will include an overview of the virus including history and current research

The human T-lymphotropic virus type 1 (HTLV-1) was the first oncogenic human retrovirus to be discovered. It was first studied in 1977. The virus can cause adult T-cell leukemia/lymphoma (ATL) and progressive nervous system condition known as HTLV-1-associated myelopathy or tropical spastic paraparesis (HAM/TSP).

Tropical spastic paraparesis (TSP), is a medical condition that causes weakness, muscle spasms, and sensory disturbance by human T-lymphotropic virus resulting in paraparesis, weakness of the legs. As the name suggests, it is most common in tropical regions, including the Caribbean

Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.[1].

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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Structure

This section will include the structure of the virus

Human T-Lymphotropic Virus is part of the Delta-type retrovirus group. HTLVs are enveloped viruses with a diameter of approximately 80–100 nm. The HTLV virions contain two covalently bound genomic RNA strands, which are complexed with the viral enzymes reverse transcriptase, integrase and protease, and the capsid proteins. The outer part of the virions consists of a membrane-associated matrix protein and a lipid layer intersected by the envelope proteins

Life Cycle

This section will include life cycle of the virus, replication, and how it infects cells

Diagnosis

This section will include the diagnosis process of this oncogenic virus and symptoms of the infection

Treatment

This section will include treatment and living with the virus and the affects of the symptoms caused by the virus

Conclusion

This section will include a summary

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Edited by [Sydney Srnka], student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2020, Kenyon College.