Leptospira noguchii: Difference between revisions
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*Include as many headings as are relevant to your microbe. Consider using the headings below, as they will allow readers to quickly locate specific information of major interest* | *Include as many headings as are relevant to your microbe. Consider using the headings below, as they will allow readers to quickly locate specific information of major interest* | ||
=3. Genome structure= | =3. Genome structure= | ||
The genome size of L. noguchii (Serovar Panama, Strain U73) is 4.7 Mb and has a GC content of 35.5% (15). The genome contains 4034 total genes with 3798 coding genes. Genes relevant to virulence factors included lipoprotein and immunoglobulin-like protein genes lipL41, lipL36, lolC/D, and ligA which are shared by L. interrogans. Several antimicrobial resistance genes are identified which includes efflux pumps (mdtA, mdtB, norM) and metal resistance genes (sugE, czcA, czcD). | |||
L. noguchii serotypes were sourced from various wild and domestic animals, such as cattle, and from human patients. Three serotypes were previously established as Bataviae, Australis, and Autumnalis and were confirmed by the sequencing of the rpoB gene (7). A recent phylogenetic study yielded sequencing results of the secY locus, identifying additional L. noguchii serogroups Panama and Pyrogenes (8). | |||
=4. Cell structure= | =4. Cell structure= | ||
Interesting features of cell structure. Can be combined with “metabolic processes” | Interesting features of cell structure. Can be combined with “metabolic processes” | ||
Revision as of 14:18, 11 December 2023
1. Classification
Higher order taxa
Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae; Leptospira
2. Description and significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
- Include as many headings as are relevant to your microbe. Consider using the headings below, as they will allow readers to quickly locate specific information of major interest*
3. Genome structure
The genome size of L. noguchii (Serovar Panama, Strain U73) is 4.7 Mb and has a GC content of 35.5% (15). The genome contains 4034 total genes with 3798 coding genes. Genes relevant to virulence factors included lipoprotein and immunoglobulin-like protein genes lipL41, lipL36, lolC/D, and ligA which are shared by L. interrogans. Several antimicrobial resistance genes are identified which includes efflux pumps (mdtA, mdtB, norM) and metal resistance genes (sugE, czcA, czcD). L. noguchii serotypes were sourced from various wild and domestic animals, such as cattle, and from human patients. Three serotypes were previously established as Bataviae, Australis, and Autumnalis and were confirmed by the sequencing of the rpoB gene (7). A recent phylogenetic study yielded sequencing results of the secY locus, identifying additional L. noguchii serogroups Panama and Pyrogenes (8).
4. Cell structure
Interesting features of cell structure. Can be combined with “metabolic processes”
5. Metabolic processes
Describe important sources of energy, electrons, and carbon (i.e. trophy) for the organism/organisms you are focusing on, as well as important molecules it/they synthesize(s).
6. Ecology
Habitat; symbiosis; contributions to the environment.
7. Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
8. Current Research
Include information about how this microbe (or related microbes) are currently being studied and for what purpose
9. References
It is required that you add at least five primary research articles (in same format as the sample reference below) that corresponds to the info that you added to this page. [Sample reference] Faller, A., and Schleifer, K. "Modified Oxidase and Benzidine Tests for Separation of Staphylococci from Micrococci". Journal of Clinical Microbiology. 1981. Volume 13. p. 1031-1035.
