Mucispirillum schaedleri

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1. Classification

a. Higher order taxa

Bacteria; Deferribacterota; Deferribacteres; Deferribacterales; Deferribacteraceae (1). Species: There is only one known species of the Mucispirillum, called Mucispirillum schaedleri.

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2. Description and significance

Mucispirillum schaedleri is a bacteria that can pose a threat to the host’s mucous layers of the colon or cecum, causing potential health complications in animals and humans. It can be found in the gut and cause intestinal disorders. Horizontal gene transfer has had a major impact on M. schaedleri's genome, highlighting its significance in determining the bacterium's function within the gut environment (2). Mucispirillum schaedleri plays an important role in the understanding of gut inflammation (3), with the majority of studies having been conducted on rodents and mice.

3. Genome structure

M. schaedleri's genome consists of 2.3 million base pairs with 31.15% GC content and 88% Protein coding region. The average coding sequence (CDS) length is 923.71 base pairs (bp), and the intergenic regions have an average length of 147.5 bp. Among these, there are a total of 2,227 CDS, encompassing 2,223 protein-coding genes. Additionally, the genome have 2 copies of 5S rRNA, 3 copies of 16S rRNA, and 2 copies of 23S rRNA, contributing to the ribosomal RNA content. A complete set of 39 tRNA genes has been identified, indicating the presence of a functional translation apparatus. Based on the recent genomic study, M. schaedleri’s genome possesses the genes of several pathways that are capable of utilizing monosaccharides, oligopeptides, amino acids, glycerol, and short-chain fatty acids (SCFAs) to generate energy (2). Results showed that the genome is shaped by horizontal gene transfer, particularly from intestinal Epsilon- and Deltaproteobacteria. These intestinal components have been linked to the most prevalent cause of human gastroenteritis, suggesting that horizontal gene transfer has a significant influence in shaping its role in the gut environment with the help of effector proteins (2).

4. Cell structure

Interesting features of cell structure. Can be combined with “metabolic processes”

5. Metabolic processes

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6. Ecology

Habitat; symbiosis; contributions to the environment.

7. Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

8. Current Research

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9. References

It is required that you add at least five primary research articles (in same format as the sample reference below) that corresponds to the info that you added to this page. [Sample reference] Faller, A., and Schleifer, K. "Modified Oxidase and Benzidine Tests for Separation of Staphylococci from Micrococci". Journal of Clinical Microbiology. 1981. Volume 13. p. 1031-1035.