Mycobacterium bovis: Difference between revisions

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==Description and significance==
==Description and significance==
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated.
“Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with world wide annual losses to agriculture of $3 billion.”(2) M. bovis is the agent responsible for bovine tuberculosis, however it can also cause the disease in humans if there is consumption of infected materials.(1) Pasteurization of milk has been a major preventative factor in stopping transmission of bovine tuberculosis in humans; however in many underdeveloped countries, where pasteurization is not practiced, there is still a concern with infection by M. bovis.(1) M. bovis AF2122/97 is a fully virulent strain that was isolated from a diseased cow in 1997.(2)
Include a picture or two (with sources) if you can find them.


==Genome structure==
==Genome structure==

Revision as of 03:56, 3 June 2007

A Microbial Biorealm page on the genus Mycobacterium bovis

Classification

Higher order taxa

Higher Order Taxa: Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex (1)

Genus

Mycobacterium bovis


NCBI: Taxonomy

Description and significance

“Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with world wide annual losses to agriculture of $3 billion.”(2) M. bovis is the agent responsible for bovine tuberculosis, however it can also cause the disease in humans if there is consumption of infected materials.(1) Pasteurization of milk has been a major preventative factor in stopping transmission of bovine tuberculosis in humans; however in many underdeveloped countries, where pasteurization is not practiced, there is still a concern with infection by M. bovis.(1) M. bovis AF2122/97 is a fully virulent strain that was isolated from a diseased cow in 1997.(2)

Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

example:

Glockner, F. O., M. Kube, M. Bauer, H. Teeling, T. Lombardot, W. Ludwig, D. Gade, A. Beck, K Borzym, K Heitmann, R. Rabus, H. Schlesner, R. Amann, and R. Reinhardt. 2003. "Complete genome sequence of the marine planctomycete Pirellula sp. strain 1." Proceedings of the National Acedemy of Sciences, vol. 100, no. 14. (8298-8303)


Edited by Steven Lada, student of Rachel Larsen and Kit Pogliano