Mycobacterium kansasii

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Classification

Domain: Bacteria; Phylum: Actinomycete; Class: Actinomycetia; Order: Mycobacteriales; Family: Mycobacteriaceae; Genus: Mycobacterium; Species: kansasii

Species

NCBI: Taxonomy

Mycobacterium kansasii

Description and Significance

Describe the appearance, habitat, etc. of the organism, and why you think it is important.

Genome Structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Circular

Cell Structure, Metabolism and Life Cycle

Interesting features of cell structure; how it gains energy; what important molecules it produces.

Ecology and Pathogenesis

M. kansasii has been cultured in many countries including Australia, Brazil, United States, Canada, and in parts of Europe. In the United States, M. kansasii is often found in midwestern and southwestern states. Like most other Non-Tuberculosis Mycobacterium (NTM) infections, infection occurs through inhalation of the bacterium in aerosols. However, this bacteria can be found in drinking water, natural waters, pipes/plumbing, and in soils. Statistically, infection is more likely to occur in urban areas than rural areas possibly due to an abundance of dirt in the air from mining or farming practices.

Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

References

Levendosky, Keith, et al. “Comprehensive Essentiality Analysis of the Mycobacterium Kansasii Genome by Saturation Transposon Mutagenesis and Deep Sequencing.” mBio, vol. 14, no. 4, pp. e00573-23. PubMed Central, https://doi.org/10.1128/mbio.00573-23. Accessed 18 Apr. 2024.

Luo, Tao, et al. “Population Genomics Provides Insights into the Evolution and Adaptation to Humans of the Waterborne Pathogen Mycobacterium Kansasii.” Nature Communications, vol. 12, no. 1, May 2021, p. 2491. www.nature.com, https://doi.org/10.1038/s41467-021-22760-6.

“Mycobacterium Kansasii.” Mycobacterium Kansasii - an Overview | ScienceDirect Topics,www.sciencedirect.com/topics/immunology-and microbiology/mycobacterium-kansasii. Accessed 18 Apr. 2024.

StatPearls. “Mycobacterium Kansasii Infection.” StatPearls, StatPearls Publishing, 8 Aug. 2023, www.statpearls.com/articlelibrary/viewarticle/25421/.

Author

Page authored by Cameron Phipps and Adrian Pena, student of Prof. Jay Lennon at Indiana University.