Mycobacterium phlei: Difference between revisions

From MicrobeWiki, the student-edited microbiology resource
No edit summary
No edit summary
Line 21: Line 21:
==Description and Significance==  
==Description and Significance==  


Early findings of Mycobacterium Phlei have reported the microorganism existing in a rod shaped, but there have also been reports of a coccoid form depending on environmental conditions. The coccoid form is the primary relaxed form of the organism and when introduced to nutrients, Mycobacterium Phlei transitions back to the rod shape (Das et al., 2016). The microorganism can usually be found in water ecosystems, forest biomes and in drinking water (Egamberdieva et al., 2011). The study of M. Phlei, enables a more comprehensive understanding of other pathogenic mycobacteria such as Mycobacterium Tuberculosis.  
Early findings of Mycobacterium Phlei or Mycolicibacterium Phlei, have reported the microorganism existing in a rod shaped, but there have also been reports of a coccoid form depending on environmental conditions. The coccoid form is the primary relaxed form of the organism and when introduced to nutrients, Mycobacterium Phlei transitions back to the rod shape (Das et al., 2016). The microorganism can usually be found in water ecosystems, forest biomes and in drinking water (Egamberdieva et al., 2011). The study of M. Phlei, enables a more comprehensive understanding of other pathogenic mycobacteria such as Mycobacterium Tuberculosis.  


==Genome Structure==  
==Genome Structure==  
Line 27: Line 27:
The size of the genome of M. Phlei is 5.64 million base pairs and encodes approximately 5,489 genes (Abdallah et al., 2012). M. phlei has a single circular chromosome (Qiu et al., 2022) In addition, the GC (guinane/cystosine) content of the genome is 69.24%, making it one of the highest among Mycobacteria. The genome also contains 2 rRNA operons, which are vital to the organisms survival (Das et al., 2016). Interestingly, M. phlei contains genes encoding for polyamine metabolism and transport, which are not found in other mycobacteria. The number of sigma factors differs from strain to strain for this fast growing microorganism (Das et al., 2016).  
The size of the genome of M. Phlei is 5.64 million base pairs and encodes approximately 5,489 genes (Abdallah et al., 2012). M. phlei has a single circular chromosome (Qiu et al., 2022) In addition, the GC (guinane/cystosine) content of the genome is 69.24%, making it one of the highest among Mycobacteria. The genome also contains 2 rRNA operons, which are vital to the organisms survival (Das et al., 2016). Interestingly, M. phlei contains genes encoding for polyamine metabolism and transport, which are not found in other mycobacteria. The number of sigma factors differs from strain to strain for this fast growing microorganism (Das et al., 2016).  


Describe the size and content of the genome.  How many chromosomes?  Circular or linear? 
Other interesting features?  What is known about its sequence?
   
   
==Cell Structure, Metabolism and Life Cycle==  
==Cell Structure, Metabolism and Life Cycle==  
M. pheli are considered to be saprophytic organisms that absorb nutients from plants (Egamberdieva et al., 2011).
Interesting features of cell structure; how it gains energy; what important molecules it produces.  
Interesting features of cell structure; how it gains energy; what important molecules it produces.  
   
   
Line 47: Line 47:


http://www.ncbi.nlm.nih.gov/Taxonomy/ NCBI
http://www.ncbi.nlm.nih.gov/Taxonomy/ NCBI
https://pubmed.ncbi.nlm.nih.gov/35727046/





Revision as of 22:35, 14 November 2022

Wiki Page Template:

This student page has not been curated.
Legend. Image credit: Name or Publication.

Classification

Bacteria, Actinobacteria, Actinomycetia, Corynebacteriales, Mycobaceriaceae, Mycolicibacterium


Species

NCBI: [https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=1007084&lvl= 3&lin=f&keep=1&srchmode=1&unlock]

Mycobacterium Phlei

Description and Significance

Early findings of Mycobacterium Phlei or Mycolicibacterium Phlei, have reported the microorganism existing in a rod shaped, but there have also been reports of a coccoid form depending on environmental conditions. The coccoid form is the primary relaxed form of the organism and when introduced to nutrients, Mycobacterium Phlei transitions back to the rod shape (Das et al., 2016). The microorganism can usually be found in water ecosystems, forest biomes and in drinking water (Egamberdieva et al., 2011). The study of M. Phlei, enables a more comprehensive understanding of other pathogenic mycobacteria such as Mycobacterium Tuberculosis.

Genome Structure

The size of the genome of M. Phlei is 5.64 million base pairs and encodes approximately 5,489 genes (Abdallah et al., 2012). M. phlei has a single circular chromosome (Qiu et al., 2022) In addition, the GC (guinane/cystosine) content of the genome is 69.24%, making it one of the highest among Mycobacteria. The genome also contains 2 rRNA operons, which are vital to the organisms survival (Das et al., 2016). Interestingly, M. phlei contains genes encoding for polyamine metabolism and transport, which are not found in other mycobacteria. The number of sigma factors differs from strain to strain for this fast growing microorganism (Das et al., 2016).


Cell Structure, Metabolism and Life Cycle

M. pheli are considered to be saprophytic organisms that absorb nutients from plants (Egamberdieva et al., 2011). Interesting features of cell structure; how it gains energy; what important molecules it produces.

Ecology and Pathogenesis

Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

References

https://dergipark.org.tr/tr/download/article-file/121072

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860684/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370867/

http://www.ncbi.nlm.nih.gov/Taxonomy/ NCBI

https://pubmed.ncbi.nlm.nih.gov/35727046/


[Sample reference] [http://ijs.sgmjournals.org/cgi/reprint/50/2/489 Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.]

Author

Page authored by _____, student of Prof. Bradley Tolar at UNC Wilmington.

[[Category:Pages edited by students of Bradley Tolar at UNC Wilmington]]