Mycoplasma haemocanis: Difference between revisions
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Describe the appearance, habitat, etc. of the organism, and why you think it is important. | Describe the appearance, habitat, etc. of the organism, and why you think it is important. | ||
''Mycoplasma haemocanis'' is a hemotrophic, gram-negative bacteria apart of the ''Mycoplasma'' genus. The species and | ''Mycoplasma haemocanis'' is a hemotrophic, gram-negative bacteria apart of the ''Mycoplasma'' genus. The species and genus is characterized by its lack of a cell wall and its small size of less than 1 µm. Formerly known as ''Haemobartonella canis'', this species is commonly associated with causing hemolytic anemia in immunocompromised canines, specifically those who have undergone a splenectomy [1]. ''M. haemocanis'' attaches to the surface of erythrocytes (red blood cells) in hosts and can be visualized in a blood smear either as single cells or "bowed-looking" chains. This species is uncultivable ''in vitro'' [2]. The bacteria has a similar resemblance to the feline equivalent ''Mycoplasma haemofelis'', which causes hemolytic anemia in cats. In a genetic comparison of the species' genomes, the two are actually concluded to be two different species infecting two distinct animals [2,3]. | ||
==Genome Structure== | ==Genome Structure== | ||
Revision as of 23:22, 13 April 2024
Classification
Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmatales; Mycoplasmataceae
Species
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NCBI: Taxonomy |
Mycoplasma haemocanis
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
Mycoplasma haemocanis is a hemotrophic, gram-negative bacteria apart of the Mycoplasma genus. The species and genus is characterized by its lack of a cell wall and its small size of less than 1 µm. Formerly known as Haemobartonella canis, this species is commonly associated with causing hemolytic anemia in immunocompromised canines, specifically those who have undergone a splenectomy [1]. M. haemocanis attaches to the surface of erythrocytes (red blood cells) in hosts and can be visualized in a blood smear either as single cells or "bowed-looking" chains. This species is uncultivable in vitro [2]. The bacteria has a similar resemblance to the feline equivalent Mycoplasma haemofelis, which causes hemolytic anemia in cats. In a genetic comparison of the species' genomes, the two are actually concluded to be two different species infecting two distinct animals [2,3].
Genome Structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
[1] Willi, B., Novacco, M., Meli, M., Wolf-Jäckel, G., Boretti, F., Wengi, N., Lutz, H., & Hofmann-Lehmann, R. (2010). Haemotropic mycoplasmas of cats and dogs: transmission, diagnosis, prevalence and importance in Europe. Schweizer Archiv fur Tierheilkunde, 152(5), 237–244. https://doi.org/10.1024/0036-7281/a000055
[2] do Nascimento, N.C., Santos, A.P., Guimaraes, A.M. et al. (2012). Mycoplasma haemocanis – the canine hemoplasma and its feline counterpart in the genomic era. Veterinary Research, 43(1), 66. https://doi.org/10.1186/1297-9716-43-66
[3] Hemotropic Mycoplasma infections in animals - circulatory system. Merck Veterinary Manual. (n.d.). https://www.merckvetmanual.com/circulatory-system/blood-parasites/hemotropic-mycoplasma-infections-in-animals
[4]
Author
Page authored by Erin Byers & Olivia Choros, students of Prof. Jay Lennon at IndianaUniversity.
