Phage Therapy for Drug-Resistant Pathogens: Difference between revisions

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In this project, I will be researching phage therapy as a defense against drug-resistant pathogens, specifically bacteria.  Typically, antibiotics are used in order to combat bacterial infections and have had a lot of success.  Although, when antibiotics are used often, bacteria is capable of developing a resistance to the drug, rendering it much less effective.  A newer potential defense of pathogens is phage therapy.  Phage therapy uses bacteriophages, which are viruses that target and infect bacteria.  Each type of bacteria is susceptible to a number of bacteriophages [1].  When using a bacteriophage to target a pathogen, bacterial lysis often occurs, leading to the breakdown of a cell’s membrane and bursting of the cell [1].  This would be a successful result in targeting a pathogen.  The use of phage therapy actually dates back to the early 1900s, even before antibiotics were discovered.  Once antibiotics were widely used, phage therapy dissipated but now that bacteria are developing drug-resistant characteristics, the use of phage therapy has gained a renewed interest and is continuously expanding. <br>
In this project, I will be researching phage therapy as a defense against drug-resistant pathogens, specifically bacteria.  Typically, antibiotics are used in order to combat bacterial infections and have had a lot of success.  Although, when antibiotics are used often, bacteria is capable of developing a resistance to the drug, rendering it much less effective.  A newer potential defense of pathogens is phage therapy.  Phage therapy uses bacteriophages, which are viruses that target and infect bacteria.  Each type of bacteria is susceptible to a number of bacteriophages <ref name=aa/>.  When using a bacteriophage to target a pathogen, bacterial lysis often occurs, leading to the breakdown of a cell’s membrane and bursting of the cell <ref name=aa/>.  This would be a successful result in targeting a pathogen.  The use of phage therapy actually dates back to the early 1900s, even before antibiotics were discovered.  Once antibiotics were widely used, phage therapy dissipated but now that bacteria are developing drug-resistant characteristics, the use of phage therapy has gained a renewed interest and is continuously expanding. <br>
Sample citations: <ref name=aa>[https://ncia.wwnorton.com/ebook-microbio5=PDF Slonczewski, J. L., & Foster, J. W. (2017). In Microbiology an evolving science. New York: W.W. Norton & Company. Retrieved March 16, 2021.]</ref>
Sample citations: <ref name=aa>[https://ncia.wwnorton.com/ebook-microbio5=PDF Slonczewski, J. L., & Foster, J. W. (2017). In Microbiology an evolving science. New York: W.W. Norton & Company. Retrieved March 16, 2021.]</ref>
<br><br>A citation code consists of a hyperlinked reference within "ref" begin and end codes.
<br><br>A citation code consists of a hyperlinked reference within "ref" begin and end codes.

Revision as of 14:01, 6 April 2021

Section

This illustration depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. The photo credit for this image belongs to Alissa Eckert, who is a medical illustrator at the CDC.


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In this project, I will be researching phage therapy as a defense against drug-resistant pathogens, specifically bacteria. Typically, antibiotics are used in order to combat bacterial infections and have had a lot of success. Although, when antibiotics are used often, bacteria is capable of developing a resistance to the drug, rendering it much less effective. A newer potential defense of pathogens is phage therapy. Phage therapy uses bacteriophages, which are viruses that target and infect bacteria. Each type of bacteria is susceptible to a number of bacteriophages [1]. When using a bacteriophage to target a pathogen, bacterial lysis often occurs, leading to the breakdown of a cell’s membrane and bursting of the cell [1]. This would be a successful result in targeting a pathogen. The use of phage therapy actually dates back to the early 1900s, even before antibiotics were discovered. Once antibiotics were widely used, phage therapy dissipated but now that bacteria are developing drug-resistant characteristics, the use of phage therapy has gained a renewed interest and is continuously expanding.
Sample citations: [1]

A citation code consists of a hyperlinked reference within "ref" begin and end codes.
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Include some current research, with at least one figure showing data.

Every point of information REQUIRES CITATION using the citation tool shown above.

Section 2

Include some current research, with at least one figure showing data.

Section 3

Include some current research, with at least one figure showing data.

Section 4

Conclusion

References



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2021, Kenyon College.